Nanoparticle–cell interactions: molecular structure of the protein corona and cellular outcomes

CC Fleischer, CK Payne - Accounts of chemical research, 2014 - ACS Publications
Conspectus The use of nanoparticles (NPs) in biology and medicine requires a molecular-
level understanding of how NPs interact with cells in a physiological environment. A critical …

Nanobiotechnology for agriculture: Smart technology for combating nutrient deficiencies with nanotoxicity challenges

G Chugh, KHM Siddique, ZM Solaiman - Sustainability, 2021 - mdpi.com
Nanobiotechnology in agriculture is a driver for modern-day smart, efficient agricultural
practices. Nanoparticles have been shown to stimulate plant growth and disease resistance …

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the …

F Wang, L Yu, MP Monopoli, P Sandin, E Mahon… - … , Biology and Medicine, 2013 - Elsevier
Nanoparticles have unique capacities of interacting with the cellular machinery and entering
cells. To be able to exploit this potential, it is essential to understand what controls the …

Adsorption and unfolding of a single protein triggers nanoparticle aggregation

S Dominguez-Medina, L Kisley, LJ Tauzin, A Hoggard… - ACS …, 2016 - ACS Publications
The response of living systems to nanoparticles is thought to depend on the protein corona,
which forms shortly after exposure to physiological fluids and which is linked to a wide array …

The intracellular destiny of the protein corona: a study on its cellular internalization and evolution

F Bertoli, D Garry, MP Monopoli, A Salvati… - ACS nano, 2016 - ACS Publications
It has been well established that the early stages of nanoparticle–cell interactions are
governed, at least in part, by the layer of proteins and other biomolecules adsorbed and …

Secondary structure of corona proteins determines the cell surface receptors used by nanoparticles

CC Fleischer, CK Payne - The Journal of Physical Chemistry B, 2014 - ACS Publications
Nanoparticles used for biological and biomedical applications encounter a host of
extracellular proteins. These proteins rapidly adsorb onto the nanoparticle surface, creating …

Super‐resolution microscopy unveils dynamic heterogeneities in nanoparticle protein corona

N Feiner‐Gracia, M Beck, S Pujals, S Tosi, T Mandal… - Small, 2017 - Wiley Online Library
The adsorption of serum proteins, leading to the formation of a biomolecular corona, is a key
determinant of the biological identity of nanoparticles in vivo. Therefore, gaining knowledge …

Nanoparticle surface charge mediates the cellular receptors used by protein–nanoparticle complexes

CC Fleischer, CK Payne - The Journal of Physical Chemistry B, 2012 - ACS Publications
Nanoparticles are increasingly important for biological applications ranging from drug
delivery to cellular imaging. In the course of these applications, nanoparticles are exposed …

ZnO-based nanofungicides: Synthesis, characterization and their effect on the coffee fungi Mycena citricolor and Colletotrichum sp.

PA Arciniegas-Grijalba, MC Patiño-Portela… - Materials Science and …, 2019 - Elsevier
In this work we compare the antifungal capacity of zinc oxide nanoparticles (ZnO-NPs)
synthesized by a chemical route and a ZnO-based nanobiohybrid obtained by green …

Nanoparticle-induced oxidation of corona proteins initiates an oxidative stress response in cells

DT Jayaram, S Runa, ML Kemp, CK Payne - Nanoscale, 2017 - pubs.rsc.org
Titanium dioxide nanoparticles (TiO2 NPs), used as pigments and photocatalysts, are
ubiquitous in our daily lives. Previous work has observed cellular oxidative stress in …