The pyrazolone structural motif is a critical element of drugs aimed at different biological end-
points. Medicinal chemistry researches have synthesized drug-like pyrazolone candidates …

Chromones, six-membered oxygen heterocycles, and pyrazoles, five-membered two-
adjacent-nitrogen-containing heterocycles, represent two important classes of biologically …

In the last decade, sonochemistry has become an interesting field of research in both
organic chemistry and pharmaceutical industry. It is well known that the sonochemical …

Background: Synthesis of substituted N'-aryl-N'-adipic acid thiourea (1-7) was, carried out
adipic acid chlorides with potassium thiocynate in situ produced isocyanate followed by …

Antibiotic resistance (AR) is the biggest concern in public health that causes tremendous
economic loss and fatalities. Clostridioides difficile is the most common cause of hospital …

Несмотря на долгую историю развития химии пиразолов, к данному классу соединений
сохраняется огромный интерес, о чем свидетельствует опубликование за последние 5 …

Thiazoles and their derivatives have long been used as precursors for the synthesis of
biologically active molecules because of the wide spectrum of activity shown by the thiazole …