LA Linkins, AL Dans, LK Moores, R Bona, BL Davidson… - Chest, 2012 - Elsevier
Background Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including …
This chapter about the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the Antithrombotic and Thrombolytic Therapy: American …
TE Warkentin, M Pai, LA Linkins - Blood, The Journal of the …, 2017 - ashpublications.org
Direct oral anticoagulants (DOACs) are attractive options for treatment of heparin-induced thrombocytopenia (HIT). We report our continuing experience in Hamilton, ON, Canada …
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …
T Bakchoul, I Marini - Hematology 2014, the American Society …, 2018 - ashpublications.org
Many drugs have been implicated in drug-induced immune thrombocytopenia (DITP). Patients with DITP develop a drop in platelet count 5 to 10 days after drug administration …
JG Kelton, TE Warkentin - Blood, The Journal of the American …, 2008 - ashpublications.org
Heparin was discovered 90 years ago, 1 and within 2 decades it was being widely used as an anticoagulant. 2 The numerous advantages of heparin lend to its broad use including its …
A Greinacher, TE Warkentin - Thrombosis and haemostasis, 2008 - thieme-connect.com
This review discusses the pharmacology and clinical applications of hirudin, a bivalent direct thrombin inhibitor (DTI). Besides the current major indication for hirudin–anticoagulation of …
TE Warkentin - Hematology 2010, the American Society of …, 2011 - ashpublications.org
Heparin-induced thrombocytopenia (HIT) is a prothrombotic drug reaction caused by platelet- activating IgG antibodies that recognize platelet factor 4 (PF4)/polyanion complexes. Platelet …
I Marini, G Uzun, K Jamal, T Bakchoul - Haematologica, 2022 - ncbi.nlm.nih.gov
Several therapeutic agents can cause thrombocytopenia by either immune-mediated or non- immune-mediated mechanisms. Non-immune-mediated thrombocytopenia is due to direct …