In metabolic conditions such as obesity and diabetes, which are associated with
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …

Nowadays, obesity is considered as a serious and growing global health problem. It is
documented that the overweight and obesity are major risk factors for a series of …

The adipose tissue microenvironment plays a key role in tumour initiation and progression
because it provides fatty acids and adipokines to tumour cells. The fatty acid-binding protein …

Group 2 innate lymphoid cells (ILC2s) are abundant in non-lymphoid tissues and increase
following infectious and inflammatory insults. In solid tumors, however, ILC2s constitute a …

Background Breast cancer is the leading female cancer type and the cause of cancer-
related mortality worldwide. Adipocytes possess important functions of energy supply …

Intermittent hypoxia (IH)-induces alterations in tumor-associated macrophages (TAMs) that
are associated with adverse cancer outcomes, as reported in patients suffering from sleep …

Malignant melanoma (MM) is an aggressive and easily metastatic cancer that is poorly
responsive to current therapy. The crosstalk between melanoma cells and tumor-associated …

The impact of metabolic stress induced by obesity on the bone marrow melanoma niche is
largely unknown. Here we employed diet induced obese mice model, where mice received …

Introduction: Obesity has increased dramatically over the last three decades. Thus,
epidemiological evidence linking obesity and cancer has ignited our interest in the …

Innate lymphoid cells (ILCs) are mostly tissue resident lymphocytes that are preferentially
enriched in barrier tissues such as the skin. Although they lack the expression of somatically …