Complex systems with many interacting nodes are inherently stochastic and best described
by stochastic differential equations. Despite increasing observation data, inferring these …

The transcellular propagation of the aberrantly modified protein tau along the functional
brain network is a key hallmark of Alzheimer's disease and related tauopathies. Inoculation …

Tau was originally identified as a microtubule associated protein, and subsequently
recognized to constitute the fibrillar assemblies found in Alzheimer disease and related …

Background: Neurodegenerative tauopathies may progress based on seeding by
pathological tau assemblies, whereby an aggregate is released from one cell, gains entry to …

Background Neurodegenerative tauopathies may progress based on seeding by
pathological tau assemblies, whereby an aggregate is released from one cell, gains entry to …

Tauopathies, including Alzheimer's disease (AD), are neurodegenerative disorders
characterized by hyperphosphorylated tau protein aggregates in the brain. In addition to …

Parameterization and a priori identifiability analysis are two interconnected steps that should
be carried out in advance of model calibration. In the first place, we propose a framework for …

This review explores Alzheimer's Disease (AD) and Frontotemporal Dementia (FTD)
focusing on the complex pathophysiology, advanced diagnostic methodologies, and …

Mon travail de thèse s' est porté principalement sur l'étude des tauopathies. Les tauopathies
sont un groupe de maladies neurodégénératives caractérisées par l'accumulation et …

Tauopathies, including Alzheimer's disease (AD), are characterized by the accumulation of
hyperphosphorylated tau proteins, which results from dysregulated tau proteostasis. Small …