Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …

Metabolic phenotyping in clinical and surgical environments

JK Nicholson, E Holmes, JM Kinross, AW Darzi… - Nature, 2012 - nature.com
Metabolic phenotyping involves the comprehensive analysis of biological fluids or tissue
samples. This analysis allows biochemical classification of a person's physiological or …

[HTML][HTML] Breath analysis as a potential and non-invasive frontier in disease diagnosis: an overview

J Pereira, P Porto-Figueira, C Cavaco, K Taunk… - Metabolites, 2015 - mdpi.com
Currently, a small number of diseases, particularly cardiovascular (CVDs), oncologic (ODs),
neurodegenerative (NDDs), chronic respiratory diseases, as well as diabetes, form a severe …

The versatile use of exhaled volatile organic compounds in human health and disease

AW Boots, JJBN van Berkel, JW Dallinga… - Journal of breath …, 2012 - iopscience.iop.org
Exhaled breath contains thousands of volatile organic compounds (VOCs) of which the
composition varies depending on health status. Various metabolic processes within the …

Clinical use of exhaled volatile organic compounds in pulmonary diseases: a systematic review

KDG Van de Kant, LJTM van der Sande, Q Jöbsis… - Respiratory …, 2012 - Springer
There is an increasing interest in the potential of exhaled biomarkers, such as volatile
organic compounds (VOCs), to improve accurate diagnoses and management decisions in …

Current breathomics—a review on data pre-processing techniques and machine learning in metabolomics breath analysis

A Smolinska, AC Hauschild, RRR Fijten… - Journal of breath …, 2014 - iopscience.iop.org
We define breathomics as the metabolomics study of exhaled air. It is a strongly emerging
metabolomics research field that mainly focuses on health-related volatile organic …

Taking your breath away: metabolomics breathes life in to personalized medicine

NJW Rattray, Z Hamrang, DK Trivedi, R Goodacre… - Trends in …, 2014 - cell.com
Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology
that centers on the capture, identification, and quantification of volatile organic compound …

Defining blood plasma and serum metabolome by GC-MS

O Kiseleva, I Kurbatov, E Ilgisonis, E Poverennaya - Metabolites, 2021 - mdpi.com
Metabolomics uses advanced analytical chemistry methods to analyze metabolites in
biological samples. The most intensively studied samples are blood and its liquid …

Profiling of volatile organic compounds in exhaled breath as a strategy to find early predictive signatures of asthma in children

A Smolinska, EMM Klaassen, JW Dallinga… - PloS one, 2014 - journals.plos.org
Wheezing is one of the most common respiratory symptoms in preschool children under six
years old. Currently, no tests are available that predict at early stage who will develop …

Volatile metabolites

DD Rowan - Metabolites, 2011 - mdpi.com
Volatile organic compounds (volatiles) comprise a chemically diverse class of low molecular
weight organic compounds having an appreciable vapor pressure under ambient …