Circadian regulation of the neuroimmune environment across the lifespan: from brain development to aging

R Chen, BN Routh, AD Gaudet… - Journal of biological …, 2023 - journals.sagepub.com
Circadian clocks confer 24-h periodicity to biological systems, to ultimately maximize energy
efficiency and promote survival in a world with regular environmental light cycles. In …

Hypoxia induces alterations in the circadian rhythm in patients with chronic respiratory diseases

M Castillejos-López, Y Romero, A Varela-Ordoñez… - Cells, 2023 - mdpi.com
The function of the circadian cycle is to determine the natural 24 h biological rhythm, which
includes physiological, metabolic, and hormonal changes that occur daily in the body. This …

Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection

MM e Cruz, M Miyazawa… - European Respiratory …, 2020 - Eur Respiratory Soc
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the aetiological agent of
the pandemic coronavirus disease 2019 (COVID-19), is a newly found member of the …

Circadian orchestration of host and gut microbiota in infection

Y Xia, X Ding, S Wang, W Ren - Biological Reviews, 2023 - Wiley Online Library
Circadian rhythms are present in almost every organism and regulate multiple aspects of
biological and physiological processes (eg metabolism, immune responses, and microbial …

Light/dark and temperature cycling modulate metabolic electron flow in Pseudomonas aeruginosa biofilms

LJ Kahl, KN Eckartt, DK Morales, A Price-Whelan… - MBio, 2022 - Am Soc Microbiol
Sunlight drives phototrophic metabolism, which affects redox conditions and produces
substrates for nonphototrophs. These environmental parameters fluctuate daily due to …

Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping

A Siebieszuk, M Sejbuk, AM Witkowska - International Journal of …, 2023 - mdpi.com
The recently observed circadian oscillations of the intestinal microbiota underscore the
profound nature of the human–microbiome relationship and its importance for health …

Immunological and inflammatory effects of infectious diseases in circadian rhythm disruption and future therapeutic directions

H Huang, A Mehta, J Kalmanovich, A Anand… - Molecular Biology …, 2023 - Springer
Background Circadian rhythm is characterised by daily variations in biological activity to
align with the light and dark cycle. These diurnal variations, in turn, influence physiological …

Circadian rhythms in infectious diseases and symbiosis

F Rijo-Ferreira, JS Takahashi - Seminars in cell & developmental biology, 2022 - Elsevier
Timing is everything. Many organisms across the tree of life have evolved timekeeping
mechanisms that regulate numerous of their cellular functions to optimize timing by …

Expression of antimicrobial peptide genes oscillates along day/night rhythm protecting mice skin from bacteria

B Bilska, A Zegar, AT Slominski… - Experimental …, 2021 - Wiley Online Library
Antimicrobial peptides (AMPs) are important components of the innate immune system and
are involved in skin protection against environmental insults and in wound healing. Herein …

Plant defence mechanisms are modulated by the circadian system

GR Butt, ZA Qayyum, MA Jones - Biology, 2020 - mdpi.com
Simple Summary The circadian clock is an endogenous time keeping mechanism found in
living organisms and their respective pathogens. Numerous studies demonstrate that …