Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

Autism is a heterogeneous syndrome defined by impairments in three core domains: social
interaction, language and range of interests. Recent work has led to the identification of …

1Autism Research Centre, Departments of Psychiatry and Experimental Psychology,
University of Cambridge, Cambridge CB2 2AH, United Kingdom, 2Department of Psychiatry …

Autism spectrum disorder (ASD) is more prevalent in males, and the mechanisms behind
this sex-differential risk are not fully understood. Two competing, but not mutually exclusive …

Fragile X syndrome (FXS) is the leading inherited form of intellectual disability and autism
spectrum disorder, and patients can present with severe behavioural alterations, including …

The fragile X syndrome, an X-linked dominant disorder with reduced penetrance, is one of
the most common forms of inherited mental retardation. The cognitive, behavioral, and …

The increased prevalence of autism spectrum disorder (ASD) and its detection during the
first 3 years of life have substantial relevance for early intervention. The purpose of this …

The FMR1 mutations can cause a variety of disabilities, including cognitive deficits, attention-
deficit/hyperactivity disorder, autism, and other socioemotional problems, in individuals with …

Autistic spectrum disorder (ASD) is accompanied by subtle and spatially distributed
differences in brain anatomy that are difficult to detect using conventional mass-univariate …

The broad variation in phenotypes and severities within autism spectrum disorders suggests
the involvement of multiple predisposing factors, interacting in complex ways with normal …