Macrophages: versatile players in renal inflammation and fibrosis
Macrophages have important roles in immune surveillance and in the maintenance of
kidney homeostasis; their response to renal injury varies enormously depending on the …
kidney homeostasis; their response to renal injury varies enormously depending on the …
Role of human macrophage polarization in inflammation during infectious diseases
C Atri, FZ Guerfali, D Laouini - International journal of molecular sciences, 2018 - mdpi.com
Experimental models have often been at the origin of immunological paradigms such as the
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
Enhanced lipid accumulation and metabolism are required for the differentiation and activation of tumor-associated macrophages
Tumor-associated macrophages (TAM) are important tumor-promoting cells. However, the
mechanisms underlying how the tumor and its microenvironment reprogram these cells …
mechanisms underlying how the tumor and its microenvironment reprogram these cells …
[HTML][HTML] The M1 and M2 paradigm of macrophage activation: time for reassessment
FO Martinez, S Gordon - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Macrophages are endowed with a variety of receptors for lineage-determining growth
factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues …
factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues …
HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy
Y Ganor, F Real, A Sennepin, CA Dutertre… - Nature …, 2019 - nature.com
Human immunodeficiency virus type 1 (HIV-1) eradication is prevented by the establishment
on infection of cellular HIV-1 reservoirs that are not fully characterized, especially in genital …
on infection of cellular HIV-1 reservoirs that are not fully characterized, especially in genital …
The HIV reservoir in monocytes and macrophages
ME Wong, A Jaworowski, AC Hearps - Frontiers in immunology, 2019 - frontiersin.org
In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
The effect of HAART-induced HIV suppression on circulating markers of inflammation and immune activation
NI Wada, LP Jacobson, JB Margolick, EC Breen… - Aids, 2015 - journals.lww.com
Objectives: To investigate the impact of HAART-induced HIV suppression on levels of 24
serological biomarkers of inflammation and immune activation. Design: A prospective cohort …
serological biomarkers of inflammation and immune activation. Design: A prospective cohort …
The role of macrophages in HIV-1 persistence and pathogenesis
Z Kruize, NA Kootstra - Frontiers in microbiology, 2019 - frontiersin.org
Current antiretroviral therapy (ART) effectively suppresses Human Immunodeficiency Virus
type 1 (HIV-1) in infected individuals. However, even long term ART does not eradicate HIV …
type 1 (HIV-1) in infected individuals. However, even long term ART does not eradicate HIV …
SOCS3 deficiency promotes M1 macrophage polarization and inflammation
H Qin, AT Holdbrooks, Y Liu, SL Reynolds… - The Journal of …, 2012 - journals.aai.org
Macrophages participate in both the amplification of inflammation at the time of injury and
downregulation of the inflammatory response to avoid excess tissue damage. These …
downregulation of the inflammatory response to avoid excess tissue damage. These …
Integrin‐mediated interactions control macrophage polarization in 3D hydrogels
Adverse immune reactions prevent clinical translation of numerous implantable devices and
materials. Although inflammation is an essential part of tissue regeneration, chronic …
materials. Although inflammation is an essential part of tissue regeneration, chronic …