Spinal metastases are an increasing societal health burden secondary to improvements in
systemic therapy. Estimates indicate that 100,000 or more people have symptomatic spine …

Purpose There is an unmet need for new treatments for many central nervous system
tumors. An expanding body of research supports the use of laser interstitial thermal therapy …

The blood–spinal cord barrier (BSCB) tightly regulates the transport of molecules from the
blood to the spinal cord. Herein, we present an approach for transient modulation of BSCB …

Background In the last years, laser interstitial thermal therapy (LITT) has started to be used
also in neurosurgical setting. Its efficacy for intracranial pathologies, namely, tumors and …

Abstract Background/Objectives: Spinal metastases are a frequent and serious complication
in cancer patients, often causing severe pain, instability, and neurological deficits. Thermal …

Laser interstitial thermal therapy (LITT) is being performed more frequently for various
lesions within neurosurgery, including epileptic foci, vascular malformations, and tumors …

Purpose The management of chordoma or chondrosarcoma involving the spine is often
challenging due to adjacent critical structures and tumor radioresistance. Spine stereotactic …

Percutaneous cryoablation (PCA) is a minimally invasive technique that has been recently
used to treat spinal metastases with a paucity of data currently available in the literature. A …

Purpose Spinal laser interstitial thermal therapy (sLITT) is a less invasive alternative to
surgery for metastatic epidural spinal cord compression. Here, we analyze outcomes of …

The surgical management of spinal metastases has unique challenges not encountered in
other aspects of spine surgery due to the needs of the oncologic patient. Among the key …