Acquired hemophilia A: a concise review

M Franchini, G Gandini… - American journal of …, 2005 - Wiley Online Library
Acquired hemophilia A is a rare but severe autoimmune bleeding disorder. It is more
frequent in the elderly and results from the presence of autoantibodies directed against …

Acquired factor VIII inhibitors

M Franchini, G Lippi - Blood, The Journal of the American …, 2008 - ashpublications.org
Acquired hemophilia A is a rare bleeding diathesis caused by autoantibodies directed
against clotting factor VIII and associated with an increased morbidity and mortality. This …

Haemostasis and pregnancy

M Franchini - Thrombosis and haemostasis, 2006 - thieme-connect.com
Normal pregnancy is associated with profound alterations in the coagulation and fibrinolytic
systems. While these physiological procoagulant changes are aimed to minimise …

Rituximab in the treatment of adult acquired hemophilia A: a systematic review

M Franchini - Critical reviews in oncology/hematology, 2007 - Elsevier
Rituximab is a monoclonal chimeric antibody to the CD20 antigen, which has proven to be
effective in the treatment of non-Hodgkin lymphomas. Recently, rituximab has also been …

Acquired haemophilia A: a review of what we know

ME Mingot-Castellano… - Journal of Blood …, 2022 - Taylor & Francis
Autoantibodies against plasma coagulation factors could be developed by some individuals
inducing severe and sometimes fatal bleedings. This clinical entity is called acquired …

Postpartum acquired factor VIII inhibitors

M Franchini - American journal of hematology, 2006 - Wiley Online Library
The development of factor VIII autoantibodies is a rare but severe complication of
pregnancy. Although the natural history of postpartum acquired hemophilia A is usually …

Laboratory, clinical and therapeutic aspects of acquired hemophilia A

M Franchini, G Targher, M Montagnana, G Lippi - Clinica Chimica Acta, 2008 - Elsevier
Acquired hemophilia A is a rare bleeding diathesis caused by autoantibodies directed
against clotting factor VIII and associated with an increased morbidity and mortality. This …

Acquired haemophilia A in the postpartum and risk of relapse in subsequent pregnancies: a systematic literature review

N Dewarrat, M Gavillet, A Angelillo‐Scherrer… - …, 2021 - Wiley Online Library
Abstract Background About 1%–5% of acquired haemophilia A cases affect mothers in the
postpartum setting. Aims This study delineates the characteristics of this disease, specific to …

NovoSeven: mode of action and use in acquired haemophilia

M Von Depka - Intensive Care Medicine, 2002 - Springer
Recombinant activated factor VII (rFVIIa,'NovoSeven') is indicated for the treatment of
spontaneous and surgical bleeding in patients with haemophilia A or B with antibodies to …

Hemofilia adquirida: epidemiología, clínica, diagnóstico y tratamiento

ME Mingot-Castellano, R Núñez… - Medicina Clínica, 2017 - Elsevier
El desarrollo de autoanticuerpos circulantes que inhiban a los factores de la coagulación
puede generar cuadros hemorrágicos graves y en ocasiones fatales. Esta entidad clínica se …