Stinging Nettle (Urtica dioica L.): Nutritional Composition, Bioactive Compounds, and Food Functional Properties

HP Devkota, KR Paudel, S Khanal, A Baral, N Panth… - Molecules, 2022 - mdpi.com
Stinging nettle (Urtica dioica L., Urticaceae) is commonly found in Asia, Africa, and Europe
and has a long history of being used as food and traditional medicine. Recently, this plant is …

The science of matcha: Bioactive compounds, analytical techniques and biological properties

HP Devkota, BP Gaire, K Hori, L Subedi… - Trends in Food Science …, 2021 - Elsevier
Background The interest in the plant-derived healthy foods, nutraceuticals, functional foods
and food supplements is increasing in recent times as potential agents in maintenance of …

In vitro anti-cancer activity of a polyherbal preparation, VEDICINALS® 9, against A549 human lung adenocarcinoma cells

KR Paudel, R Rajput, G De Rubis, VSRR Allam… - … -Research and Practice, 2023 - Elsevier
Purpose Non-small cell lung cancer (NSCLC) is among the leading causes of morbidity and
mortality worldwide. Despite the availability of several treatment options, the five-year …

Emerging role of tumor suppressing microRNAs as therapeutics in managing Non-small cell lung cancer

S Singh, S Saxena, H Sharma, KR Paudel… - … -Research and Practice, 2024 - Elsevier
Lung cancer (LC) is the second leading cause of death across the globe after breast cancer.
There are two types of LC viz. small cell lung cancer (SCLC) and non-small cell lung cancer …

Bioactive chemical constituents and pharmacological activities of Ponciri fructus

G Lamichhane, J Pandey, HP Devkota - Molecules, 2022 - mdpi.com
Ponciri Fructus is a crude drug obtained from the dried immature fruits of Poncirus trifoliata
(L). Raf.(Syn. Citrus trifoliata L.). This study aims to compile and analyze the ethnomedicinal …

Antioxidant genes in cancer and metabolic diseases: Focusing on Nrf2, Sestrin, and heme oxygenase 1

J Shrestha, KR Limbu, RB Chhetri… - … journal of biological …, 2024 - pmc.ncbi.nlm.nih.gov
Reactive oxygen species are involved in the pathogenesis of cancers and metabolic
diseases, including diabetes, obesity, and fatty liver disease. Thus, inhibiting the generation …

[HTML][HTML] Therapeutic potential of 18-β-glycyrrhetinic acid-loaded poly (lactic-co-glycolic acid) nanoparticles on cigarette smoke-induced in-vitro model of COPD

T El Sherkawi, AB Saeid, S Yeung… - … -Research and Practice, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is strongly linked to cigarette smoke, which
contains toxins that induce oxidative stress and airway inflammation, ultimately leading to …

[HTML][HTML] Computational and biological approaches in repurposing ribavirin for lung cancer treatment: Unveiling antitumorigenic strategies

KR Paudel, M Singh, G De Rubis, P Kumbhar… - Life Sciences, 2024 - Elsevier
Lung cancer is among leading causes of death worldwide. The five-year survival rate of this
disease is extremely low (17.8%), mainly due to difficult early diagnosis and to the limited …

Plant-based therapeutics for chronic obstructive pulmonary diseases: Nanoformulation strategies to overcome delivery challenges

S Kokkinis, M Singh, KR Paudel, G De Rubis, AB Saeid… - Food Bioscience, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a widespread global health problem
marked by increasing airflow limitation and chronic airway inflammation. Conventional …

Chungtaejeon (CTJ) inhibits adhesion and migration of VSMC through cytoskeletal remodeling pathway

KR Paudel, N Panth, DW Kim, R Karki - Heliyon, 2024 - cell.com
Introduction Vascular remodeling is crucial for the progression of vascular disease such as
atherosclerosis. We utilize the in vitro experimental model of atherosclerosis to elucidate the …