Infrequent intranasal oxytocin followed by positive social interaction improves symptoms in autistic children: a pilot randomized clinical trial

J Le, L Zhang, W Zhao, S Zhu, C Lan, J Kou… - Psychotherapy and …, 2022 - karger.com
Introduction: There are currently no approved drug interventions for social behavior
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …

Systematic review: pain, cognition, and cardioprotection—unpacking oxytocin's contributions in a sport context

P Szabó, S Bonet, R Hetényi, D Hanna… - Frontiers in …, 2024 - frontiersin.org
Introduction This systematic review investigates the interplay between oxytocin and
exercise; in terms of analgesic, anti-inflammatory, pro-regenerative, and cardioprotective …

Neural and behavioral evidence for oxytocin's facilitatory effects on learning in volatile and stable environments

M Zhou, S Zhu, T Xu, J Wang, Q Zhuang… - Communications …, 2024 - nature.com
Outcomes of past decisions profoundly shape our behavior. However, choice-outcome
associations can become volatile and adaption to such changes is of importance. The …

Oxytocin modulates neurocomputational mechanisms underlying prosocial reinforcement learning

D Martins, P Lockwood, J Cutler, R Moran… - Progress in …, 2022 - Elsevier
Humans often act in the best interests of others. However, how we learn which actions result
in good outcomes for other people and the neurochemical systems that support this …

Effects of oxytocin administration on non-social executive functions in humans: A preregistered systematic review and meta-analysis

H Kang, BD Glaser, AI Sartorius, K Audunsdottir… - Molecular …, 2025 - nature.com
Background Oxytocin has received considerable research attention for its role in affiliative
behaviors, particularly regarding its pro-social effects. More recent evidence has pointed to a …

Oxytocin, but not vasopressin, decreases willingness to harm others by promoting moral emotions of guilt and shame

X Zheng, J Wang, X Yang, L Xu, B Becker… - Molecular …, 2024 - nature.com
Prosocial and moral behaviors have overlapping neural systems and can both be affected in
a number of psychiatric disorders, although whether they involve similar neurochemical …

Kuramoto model-based analysis reveals oxytocin effects on brain network dynamics

S Zheng, Z Liang, Y Qu, Q Wu, H Wu… - International Journal of …, 2022 - World Scientific
The oxytocin effects on large-scale brain networks such as Default Mode Network (DMN)
and Frontoparietal Network (FPN) have been largely studied using fMRI data. However …

An evolutionary timeline of the oxytocin signaling pathway

AM Sartorius, J Rokicki, S Birkeland, F Bettella… - Communications …, 2024 - nature.com
Oxytocin is a neuropeptide associated with both psychological and somatic processes like
parturition and social bonding. Although oxytocin homologs have been identified in many …

[HTML][HTML] L-DOPA and oxytocin influence the neurocomputational mechanisms of self-benefitting and prosocial reinforcement learning

M Jansen, PL Lockwood, J Cutler, ERA de Bruijn - NeuroImage, 2023 - Elsevier
Humans learn through reinforcement, particularly when outcomes are unexpected. Recent
research suggests similar mechanisms drive how we learn to benefit other people, that is …

Oxytocinergic modulation of stress-associated amygdala-hippocampus pathways in humans is mediated by serotonergic mechanisms

C Lan, C Liu, K Li, Z Zhao, J Yang, Y Ma… - International Journal …, 2022 - academic.oup.com
Background The hypothalamic neuropeptide oxytocin (OXT) may exert anxiolytic and stress-
reducing actions via modulatory effects on amygdala circuits. Animal models and initial …