Retinoic acid (RA) signalling has a central role during vertebrate development. RA
synthesized in specific locations regulates transcription by interacting with nuclear RA …

Retinoids are ubiquitous signaling molecules that influence nearly every cell type, exert
profound effects on development, and complement cancer chemotherapeutic regimens. All …

An increasing recognition has emerged of the complexities of the global health agenda—
specifically, the collision of infections and noncommunicable diseases and the dual burden …

Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular
insight into their distinct roles has remained elusive. Using gene expression data combined …

The vitamin A (retinol) metabolite, all-trans retinoic acid (RA), is a signaling molecule that
plays key roles in the development of the body plan and induces the differentiation of many …

Hox genes controlling motor neuron subtype identity are expressed in rostrocaudal patterns
that are spatially and temporally collinear with their chromosomal organization. Here we …

The epigenetic phenomena refer to heritable changes in gene expression other than those
in the DNA sequence, such as DNA methylation and histone modifications. Major research …

Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

Retinoic acid (RA), the active derivative of vitamin A, a fat-soluble vitamin, plays key roles in
cell growth and differentiation by activating nuclear receptors, RARs (α, β and γ), which are …