Toxoplasma gondii and Plasmodium falciparum are important human pathogens. These
parasites and many of their apicomplexan relatives undergo a complex developmental …

The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …

Theileria are economically important, intra-cellular protozoa, transmitted by ixodid ticks,
which infect wild and domestic ruminants. In the mammalian host, parasites infect leukocytes …

The major heat shock protein, Hsp70, can protect against cell death by directly interfering
with mitochondrial apoptosis pathways. However, Hsp70 also sensitizes cells to certain …

Tremendous progress has been made over the last ten years on East Coast fever (ECF)
research. Publication of a reference genome sequence of Theileria parva, the causative …

Upregulation of the matrix metalloproteinase (MMP)–9 plays a central role in tumor
progression and metastasis by stimulating cell migration, tumor invasion, and angiogenesis …

Protozoan parasites can infect the human intestinal tract causing serious diseases. In the
following article, we focused on the three most prominent intestinal protozoan pathogens …

Apicomplexans are pathogens responsible for malaria, toxoplasmosis, and crytposporidiosis
in humans, and a wide range of livestock diseases. These unicellular eukaryotes are …

Pathogens have evolved strategies to promote their survival by dramatically modifying the
transcriptional profile and protein content of the host cells they infect. Modifications of the …

The genus Theileria includes tick-transmitted apicomplexan parasites of ruminants with
substantial economic impact in endemic countries. Some species, including Theileria parva …