Prediction of HIV drug resistance by combining sequence and structural properties
Z Khalid, OU Sezerman - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
Drug resistance is a major obstacle faced by therapist in treating HIV infected patients. The
reason behind these phenomena is either protein mutation or the changes in gene …
reason behind these phenomena is either protein mutation or the changes in gene …
Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists
NR Wurtz, JA Johnson, A Viet, PS Shirude… - ACS Medicinal …, 2022 - ACS Publications
Formyl peptide receptor 2 (FPR2) agonists have shown efficacy in inflammatory-driven
animal disease models and have the potential to treat a range of diseases. Many reported …
animal disease models and have the potential to treat a range of diseases. Many reported …
Amino acid preferences at neddylation sites
AS Yavuz, NB Sözer, U Sezerman - 2014 - research.sabanciuniv.edu
Neddylation is a dynamic post-translational modification in which NEDD8 proteins are
covalently attached to the target site lysine residue. Neddylation may affect a target protein's …
covalently attached to the target site lysine residue. Neddylation may affect a target protein's …