Developments toward diagnostic breast cancer imaging using near-infrared optical measurements and fluorescent contrast agents1

DJ Hawrysz, EM Sevick-Muraca - Neoplasia, 2000 - Elsevier
The use of near-infrared (NIR) light to interrogate deep tissues has enormous potential for
molecular-based imaging when coupled with NIR excitable dyes. More than a decade has …

Optical imaging modalities for biomedical applications

AP Dhawan, B D'Alessandro… - IEEE Reviews in …, 2010 - ieeexplore.ieee.org
Optical photographic imaging is a well known imaging method that has been successfully
translated into biomedical applications such as microscopy and endoscopy. Although …

Imaging the body with diffuse optical tomography

DA Boas, DH Brooks, EL Miller… - IEEE signal …, 2001 - ieeexplore.ieee.org
Diffuse optical tomography (DOT) is an ongoing medical imaging modality in which tissue is
illuminated by near-infrared light from an array of sources, the multiply-scattered light which …

Optical tomography using the time-independent equation of radiative transfer—Part 1: forward model

AD Klose, U Netz, J Beuthan, AH Hielscher - Journal of Quantitative …, 2002 - Elsevier
The presented study consists of two parts. The overall goal is to introduce and
experimentally test a novel optical tomographic imaging algorithm that is based on the …

Fluorescence optical diffusion tomography

AB Milstein, S Oh, KJ Webb, CA Bouman, Q Zhang… - Applied Optics, 2003 - opg.optica.org
A nonlinear, Bayesian optimization scheme is presented for reconstructing fluorescent yield
and lifetime, the absorption coefficient, and the diffusion coefficient in turbid media, such as …

In vitro determination of normal and neoplastic human brain tissue optical properties using inverse adding-doubling

SC Gebhart, WC Lin… - Physics in Medicine & …, 2006 - iopscience.iop.org
To complement a project towards the development of real-time optical biopsy for brain tissue
discrimination and surgical resection guidance, the optical properties of various brain …

Improvement of image quality in diffuse optical tomography by use of full time-resolved data

F Gao, H Zhao, Y Yamada - Applied optics, 2002 - opg.optica.org
In the field of diffuse optical tomography (DOT), it is widely accepted that time-resolved (TR)
measurement can provide the richest information on photon migration in a turbid medium …

Optical diffusion tomography by iterative-coordinate-descent optimization in a Bayesian framework

JC Ye, KJ Webb, CA Bouman, RP Millane - JOSA A, 1999 - opg.optica.org
Frequency-domain diffusion imaging uses the magnitude and phase of modulated light
propagating through a highly scattering medium to reconstruct an image of the spatially …

Three-dimensional diffuse optical mammography with ultrasound localization in a human subject

MJ Holboke, BJ Tromberg, X De Li… - Journal of …, 2000 - spiedigitallibrary.org
We describe an approach that combines clinical ultrasound and photon migration
techniques to enhance the sensitivity and information content of diffuse optical tomography …

Nonlinear multigrid algorithms for Bayesian optical diffusion tomography

JC Ye, CA Bouman, KJ Webb… - IEEE Transactions on …, 2001 - ieeexplore.ieee.org
Optical diffusion tomography is a technique for imaging a highly scattering medium using
measurements of transmitted modulated light. Reconstruction of the spatial distribution of the …