Vitamin D supplementation and allergic diseases during childhood: a systematic review and meta-analysis

Q Li, Q Zhou, G Zhang, X Tian, Y Li, Z Wang, Y Zhao… - Nutrients, 2022 - mdpi.com
We performed a systematic review and meta-analysis to investigate the effects of vitamin D
(VitD) supplementation on children with allergic diseases. MEDLINE, Embase, Web of …

A single-cell atlas of the human healthy airways

M Deprez, LE Zaragosi, M Truchi… - American journal of …, 2020 - atsjournals.org
Rationale: The respiratory tract constitutes an elaborate line of defense that is based on a
unique cellular ecosystem. Objectives: We aimed to investigate cell population distributions …

Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures

S Ruiz García, M Deprez, K Lebrigand… - …, 2019 - journals.biologists.com
The upper airway epithelium, which is mainly composed of multiciliated, goblet, club and
basal cells, ensures proper mucociliary function and can regenerate in response to assaults …

Sex plays a multifaceted role in asthma pathogenesis

T Miyasaka, K Dobashi-Okuyama, K Kawakami… - Biomolecules, 2022 - mdpi.com
Sex is considered an important risk factor for asthma onset and exacerbation. The
prevalence of asthma is higher in boys than in girls during childhood, which shows a reverse …

Early-life exposure to air pollution associated with food allergy in children: Implications for 'one allergy'concept

X Zhang, C Lu, Y Li, D Norbäck, P Murthy, RJ Sram… - Environmental …, 2023 - Elsevier
Background The rapid increase of food allergy (FA) has become the “second wave” of
allergy epidemic and is now a major global public health concern. Mounting evidence …

Manifesto on united airways diseases (UAD): an Interasma (global asthma association–GAA) document

A Tiotiu, P Novakova, I Baiardini, A Bikov… - Journal of …, 2022 - Taylor & Francis
Objective: The large amount of evidence and the renewed interest in upper and lower
airways involvement in infectious and inflammatory diseases has led Interasma (Global …

An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions

J Routhier, S Pons, ML Freidja, V Dalstein… - Nature …, 2021 - nature.com
Abstract Chronic Obstructive Pulmonary Disease is a generally smoking-linked major cause
of morbidity and mortality. Genome-wide Association Studies identified a locus including a …

Tangeretin promotes regulatory T cell differentiation by inhibiting Notch1/Jagged1 signaling in allergic rhinitis

S Xu, YG Kong, WE Jiao, R Yang, YL Qiao, Y Xu… - International …, 2019 - Elsevier
Background and objective Tangeretin demonstrates broad anti-inflammatory effects. The
present study aimed to assess whether tangeretin functions in regulating T-regulatory cells …

Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD

R Belgacemi, E Luczka, J Ancel, Z Diabasana… - …, 2020 - thelancet.com
Background Hedgehog (HH) pathway is constantly under scrutiny in the context of organ
development. Lung morphogenesis requires HH signalling which participates thereafter to …

Clinical features and nasal inflammation in asthma and allergic rhinitis

M Chen, Y Ge, W Lin, H Ying, W Zhang… - Clinical and …, 2022 - academic.oup.com
Asthma and allergic rhinitis (AR) are widely considered to be the most common chronic
inflammatory disorders. This study was performed to investigate the clinical features …