Networking brainstem and basal ganglia circuits for movement

S Arber, RM Costa - Nature Reviews Neuroscience, 2022 - nature.com
The execution and learning of diverse movements involve neuronal networks distributed
throughout the nervous system. The brainstem and basal ganglia are key for processing …

Fluorescence imaging of large-scale neural ensemble dynamics

TH Kim, MJ Schnitzer - Cell, 2022 - cell.com
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

Neural circuit basis of placebo pain relief

C Chen, JK Niehaus, F Dinc, KL Huang, AL Barnette… - Nature, 2024 - nature.com
Placebo effects are notable demonstrations of mind–body interactions,. During pain
perception, in the absence of any treatment, an expectation of pain relief can reduce the …

Diversity and dynamism in the cerebellum

CI De Zeeuw, SG Lisberger, JL Raymond - Nature neuroscience, 2021 - nature.com
The past several years have brought revelations and paradigm shifts in research on the
cerebellum. Historically viewed as a simple sensorimotor controller with homogeneous …

Activity map of a cortico-cerebellar loop underlying motor planning

J Zhu, H Hasanbegović, LD Liu, Z Gao, N Li - Nature neuroscience, 2023 - nature.com
The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown
how the two structures organize into functional networks to mediate specific behaviors. Here …

Cortical pattern generation during dexterous movement is input-driven

BA Sauerbrei, JZ Guo, JD Cohen, M Mischiati, W Guo… - Nature, 2020 - nature.com
The motor cortex controls skilled arm movement by sending temporal patterns of activity to
lower motor centres. Local cortical dynamics are thought to shape these patterns throughout …

The thalamus integrates the macrosystems of the brain to facilitate complex, adaptive brain network dynamics

JM Shine - Progress in neurobiology, 2021 - Elsevier
The human brain is a complex, adaptive system comprised of billions of cells with trillions of
connections. The interactions between the elements of the system oppose this seemingly …

Reward signals in the cerebellum: origins, targets, and functional implications

D Kostadinov, M Häusser - Neuron, 2022 - cell.com
The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …

Universal transform or multiple functionality? Understanding the contribution of the human cerebellum across task domains

J Diedrichsen, M King, C Hernandez-Castillo… - Neuron, 2019 - cell.com
An impressive body of research over the past 30 years has implicated the human
cerebellum in a broad range of functions, including motor control, perception, language …

Emergent reliability in sensory cortical coding and inter-area communication

S Ebrahimi, J Lecoq, O Rumyantsev, T Tasci, Y Zhang… - Nature, 2022 - nature.com
Reliable sensory discrimination must arise from high-fidelity neural representations and
communication between brain areas. However, how neocortical sensory processing …