[HTML][HTML] Liposomes for enhanced bioavailability of water-insoluble drugs: In vivo evidence and recent approaches

MK Lee - Pharmaceutics, 2020 - mdpi.com
It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …

Therapeutic applications of herbal/synthetic/bio-drug in oral cancer: An update

SA Mosaddad, K Beigi, T Doroodizadeh… - European Journal of …, 2021 - Elsevier
Oral cancer, as one of the most prevalent and invasive cancers that invade local tissue, can
cause metastasis, and have high mortality. In 2018, around 355,000 worldwide oral cancers …

Sensing the scent of death: modulation of microRNAs by curcumin in gastrointestinal cancers

M Ashrafizadeh, A Zarrabi, M Hashemipour… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …

[HTML][HTML] Anti-viral potential and modulation of Nrf2 by curcumin: pharmacological implications

M Rahban, M Habibi-Rezaei, M Mazaheri, L Saso… - Antioxidants, 2020 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an essential transcription factor that
maintains the cell's redox balance state and reduces inflammation in different adverse …

Demethoxylation of curcumin enhances its inhibition on human and rat 17β-hydroxysteroid dehydrogenase 3: QSAR structure-activity relationship and in silico …

Z Ji, J Sang, H Wang, M Xia, T Hao, L Chen… - Food and Chemical …, 2024 - Elsevier
Curcuminoids have many pharmacological effects. They or their metabolites may have side
effects by suppressing 17β-hydroxysteroid dehydrogenase 3 (17β-HSD3). Herein, we …

An update on potential molecular biomarkers of dietary phytochemicals targeting lung cancer interception and prevention

RM Peter, PJ Chou, A Shannar, K Patel, Y Pan… - Pharmaceutical …, 2023 - Springer
Since ancient times, dietary phytochemicals are known for their medicinal properties. They
are broadly classified into polyphenols, terpenoids, alkaloids, phytosterols, and organosulfur …

Phenylboronic acid-based core–shell drug delivery platform clasping 1, 3-dicarbonyl compounds by a coordinate interaction

S Jung, J Lee, WJ Kim - Biomaterials Science, 2021 - pubs.rsc.org
Along with the successful commercialization of chemotherapeutics, such as doxorubicin and
paclitaxel, numerous natural compounds have been investigated for clinical applications …

Curcumin inhibits human leiomyoma xenograft tumor growth and induces dissolution of the extracellular matrix

M Malik, JL Britten, A DeAngelis, C Sitler, S Moran… - F&S Science, 2023 - Elsevier
Objective To determine whether a curcumin-supplemented diet would prevent and/or treat
uterine leiomyoma growth in our mouse xenograft model. Design Animal study. Setting …

[HTML][HTML] Kinetic characteristics of curcumin and germacrone in rat and human liver microsomes: involvement of CYP enzymes

S Su, H Wu, J Zhou, G Yuan, H Wang, J Feng - Molecules, 2022 - mdpi.com
Curcumin and germacrone, natural products present in the Zingiberaceae family of plants,
have several biological properties. Among these properties, the anti-NSCLC cancer action is …

[HTML][HTML] The in vivo study on antioxidant activity of wendan decoction in treating hyperlipidemia: a pharmacokinetic-pharmacodynamic (PK-PD) model

N Xu, M Ijaz, Y Shu, P Wang, L Ma, P Wang… - Frontiers in …, 2024 - frontiersin.org
Background: Wendan Decoction (WDD) is a six-herb Chinese medicine recipe that was first
mentioned in about 652 AD. It is frequently used to treat hyperlipidemic patients' clinical …