Synapses are intercellular junctions specialized for fast, point-to-point information transfer
from a presynaptic neuron to a postsynaptic cell. At a synapse, a presynaptic terminal …

The brain processes information by transmitting signals at synapses, which connect neurons
into vast networks of communicating cells. In these networks, synapses not only transmit …

Autism spectrum disorders (ASDs) are childhood neurodevelopmental disorders with
complex genetic origins,,,. Previous studies focusing on candidate genes or genomic …

Structural variation (copy number variation [CNV] including deletion and duplication,
translocation, inversion) of chromosomes has been identified in some individuals with …

Although the neurobiology of autism has been studied for more than two decades, the
majority of these studies have examined brain structure 10, 20, or more years after the onset …

Autism spectrum disorders (ASDs) are characterized by impairments in social behaviors that
are sometimes coupled to specialized cognitive abilities. A small percentage of ASD patients …

Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions.
The genetic architecture of ASDs is complex, requiring large samples to overcome …

Autism spectrum disorder (ASD) is a severe neuropsychiatric disease with strong genetic
underpinnings. However, genetic contributions to autism are extremely heterogeneous, with …

Synaptogenesis, the generation and maturation of functional synapses between nerve cells,
is an essential step in the development of neuronal networks in the brain. It is thought to be …

Neuroligins (NLs) are a family of neural cell-adhesion molecules that are involved in
excitatory/inhibitory synapse specification. Multiple members of the NL family (including …