HIF is a transcription factor that plays an essential role in the cellular response to low
oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In …

Leishmania are protozoan parasites that predominantly reside in myeloid cells within their
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …

Oxygen (O 2) availability is a key factor regulating microbiota composition and the
homeostatic function of cells in the intestinal mucosa of vertebrates. Microbiota-derived …

Abstract Th17-polarized CD4+ effector T-cells together with their immunosuppressive
regulatory T-cell (Treg) counterparts, with transcriptional profiles governed by the lineage …

Functional components including β-glucan, dietary fiber, resistant starch and polyphenols
extracted from various coarse cereals have been reported to prevent high-fat diet (HFD) …

Leishmaniasis is endemic to the tropical and subtropical regions of the world and is
transmitted by the bite of an infected sand fly. The multifaceted interactions between …

Fatty acid metabolism, particularly fatty acid synthesis, is a very important cellular
physiological process in which nutrients are used for energy storage and biofilm synthesis …

Intermediates of both cholesterol synthesis and cholesterol metabolism can have diverse
roles in the control of cellular processes that go beyond the control of cholesterol …

Moringa oleifera is a commonly used plant with high nutritional and medicinal values. M.
oleifera leaves are considered a new food resource in China. However, the biological …

A key point of immunity against protozoan Leishmania parasites is the development of an
optimal T cell response, which includes a low apoptotic rate, high proliferative activity and …