Multimodality optical imaging probes have emerged as powerful tools that improve detection
sensitivity and accuracy, important in disease diagnosis and treatment. In this review, we …

Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

Polymethine cyanine dyes have been widely recognized as promising chemical tools for a
range of life science and biomedical applications, such as fluorescent staining of DNA and …

Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

Near-infrared (NIR) probes are ideal for fluorescence labeling and imaging of biological
targets in living animals. However, the instability of common NIR dyes hampers the …

Due to their excellent fluorescence properties and biological function, cyanine dyes have
been widely applied in biological imaging. Heptamethine cyanine (Cy7) dyes, as a type of …

The clinical applications of positron emission tomography (PET) imaging pharmaceuticals
have increased tremendously over the past several years since the approval of 18fluorine …

Because positron emission tomography (PET) and optical imaging are very complementary,
the combination of these two imaging modalities is very enticing in the oncology field. Such …

Noninvasive fluorescent imaging requires far-red and near-infrared fluorescent proteins for
deeper imaging. Near-infrared light penetrates biological tissue with blood vessels due to …

Positron emission tomography (PET)–fluorescence imaging is an emerging field of
multimodality imaging seeking to attain synergy between the two techniques. The probes …