Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer's disease

GP Morris, IA Clark, B Vissel - Acta neuropathologica, 2018 - Springer
The dominant hypothesis of Alzheimer's disease (AD) aetiology, the neuropathological
guidelines for diagnosing AD and the majority of high-profile therapeutic efforts, in both …

Neuropsychological measures that predict progression from mild cognitive impairment to Alzheimer's type dementia in older adults: a systematic review and meta …

S Belleville, C Fouquet, C Hudon… - Neuropsychology …, 2017 - Springer
This study aimed to determine the extent to which cognitive measures can predict
progression from mild cognitive impairment (MCI) to Alzheimer's type dementia (AD), assess …

Transfer learning assisted classification and detection of Alzheimer's disease stages using 3D MRI scans

M Maqsood, F Nazir, U Khan, F Aadil, H Jamal… - Sensors, 2019 - mdpi.com
Alzheimer's disease effects human brain cells and results in dementia. The gradual
deterioration of the brain cells results in disability of performing daily routine tasks. The …

Subjective cognitive impairment and affective symptoms: a systematic review

NL Hill, J Mogle, R Wion, E Munoz… - The …, 2016 - academic.oup.com
Abstract Purpose of Study: Subjective cognitive impairment (SCI) has been argued to reflect
affective symptoms (ie, depression and anxiety) rather than actual cognitive issues. Although …

A deep feature-based real-time system for Alzheimer disease stage detection

H Nawaz, M Maqsood, S Afzal, F Aadil… - Multimedia Tools and …, 2021 - Springer
The origin of dementia can be largely attributed to Alzheimer's disease (AD). The
progressive nature of AD causes the brain cell deterioration that eventfully leads to physical …

Is dysregulation of the HPA-axis a core pathophysiology mediating co-morbid depression in neurodegenerative diseases?

X Du, TY Pang - Frontiers in psychiatry, 2015 - frontiersin.org
There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …

A data augmentation-based framework to handle class imbalance problem for Alzheimer's stage detection

S Afzal, M Maqsood, F Nazir, U Khan, F Aadil… - IEEE …, 2019 - ieeexplore.ieee.org
Alzheimer's Disease (AD) is the most common form of dementia. It gradually increases from
mild stage to severe, affecting the ability to perform common daily tasks without assistance. It …

Multi-class Alzheimer's disease classification using image and clinical features

T Altaf, SM Anwar, N Gul, MN Majeed… - … Signal Processing and …, 2018 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia, which results in memory
related issues in subjects. An accurate detection and classification of AD alongside its …

Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer's disease

N Corriveau-Lecavalier, LR Barnard, J Lee… - Cerebral …, 2023 - academic.oup.com
Dysexecutive Alzheimer's disease (dAD) manifests as a progressive dysexecutive syndrome
without prominent behavioral features, and previous studies suggest clinico-radiological …

The comprehensive assessment of neurodegeneration and dementia: Canadian cohort study

H Chertkow, M Borrie, V Whitehead… - Canadian Journal of …, 2019 - cambridge.org
Background: The Comprehensive Assessment of Neurodegeneration and Dementia
(COMPASS-ND) cohort study of the Canadian Consortium on Neurodegeneration in Aging …