Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Targeting autophagy using natural compounds for cancer prevention and therapy

S Deng, MK Shanmugam, AP Kumar, CT Yap, G Sethi… - Cancer, 2019 - Wiley Online Library
Autophagy, also known as macroautophagy, is a tightly regulated process involved in the
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …

Ursolic acid—a pentacyclic triterpenoid with a wide spectrum of pharmacological activities

Ł Woźniak, S Skąpska, K Marszałek - Molecules, 2015 - mdpi.com
Ursolic acid (UA) is a natural terpene compound exhibiting many pharmaceutical properties.
In this review the current state of knowledge about the health-promoting properties of this …

[PDF][PDF] Ursolic acid in health and disease

DY Seo, SR Lee, JW Heo, MH No… - The Korean journal …, 2018 - synapse.koreamed.org
Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables.
There is a growing interest in UA because of its beneficial effects, which include anti …

Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies

MK Shanmugam, X Dai, AP Kumar, BKH Tan… - Biochemical …, 2013 - Elsevier
Discovery of bioactive molecules and elucidation of their molecular mechanisms open up an
enormous opportunity for the development of improved therapy for different inflammatory …

Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties

ST Cargnin, SB Gnoatto - Food Chemistry, 2017 - Elsevier
Apple juice production generates a large amount of residue comprising mainly peels, seeds,
and pulp, known as apple pomace. In the global context, Brazil ranks 11th in apple …

[HTML][HTML] Perspectives on natural compounds in chemoprevention and treatment of cancer: an update with new promising compounds

A Haque, D Brazeau, AR Amin - European Journal of Cancer, 2021 - Elsevier
Cancer is the second deadliest disease worldwide. Although recent advances applying
precision treatments with targeted (molecular and immune) agents are promising, the …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy

SR Lin, YS Fu, MJ Tsai, H Cheng, CF Weng - International Journal of …, 2017 - mdpi.com
Accumulated evidence indicates that autophagy is a response of cancer cells to various anti-
cancer therapies. Autophagy is designated as programmed cell death type II, and is …

Ursolic acid: A systematic review of its pharmacology, toxicity and rethink on its pharmacokinetics based on PK-PD model

Q Sun, M He, M Zhang, S Zeng, L Chen, L Zhou, H Xu - Fitoterapia, 2020 - Elsevier
Ursolic acid (UA) is a natural pentacyclic triterpenoid compound existing in various
traditional Chinese medicinal herbs, and it possesses diverse pharmacological actions and …