Despite the recent progress in cancer management approaches, the mortality rate of cancer
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …

MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …

Functional studies of the RNA N 6-methyladenosine (m6A) modification have been limited
by an inability to map individual m6A-modified sites in whole transcriptomes. To enable such …

Background: Cardiosphere-derived cells (CDCs) confer cardioprotection in acute
myocardial infarction by distinctive macrophage (Mϕ) polarization. Here we demonstrate …

Since acute myeloid leukemia (AML) is characterized by the blockade of hematopoietic
differentiation and cell death, we interrogated RIPK3 signaling in AML development. Genetic …

Background The oral cavity is a complex environment in which periodontal tissue is
constantly stimulated by external microorganisms and mechanical forces. Proper …

Exosomes are paracrine regulators of the tumor microenvironment and contain complex
cargo. We previously reported that exosomes released from acute myeloid leukemia (AML) …

Long non-coding RNAs (lncRNAs) are involved in multiple cellular events, as well as in
tumorigenesis. Colon cancer-associated transcript-1 (CCAT1) gene encodes an lncRNA …

MicroRNAs (miRNAs) are currently experiencing a renewed peak of attention not only as
diagnostics but also especially as highly promising novel targets or tools for clinical therapy …

Dysregulation of microRNAs (miRNAs) is associated with the occurrence and development
of breast cancer. In this research, we explored the involvement of miR-181a-5p in the …