G protein-coupled receptors are the target of more than 30% of all FDA-approved drug
therapies. Though the purinergic P2 receptors have been an attractive target for therapeutic …

Chronic pain in temporomandibular disorder (TMD) is a common health problem.
Cumulating evidence indicates that the etiology of TMD pain is complex with multifactorial …

Purinergic signaling system plays a pivotal role in the trigeminal ganglion (TG) which is a
primary sensory tissue in vertebrate nervous systems involving orofacial nociception and …

Objectives The underlying mechanism of masseter muscle pain hypersensitivity by
sustained masseter muscle contraction (SMMC) is not well understood. This study aimed to …

Physiology of orofacial pain pathways embraces primary afferent neurons, pathologic
changes in the trigeminal ganglion, brainstem nociceptive neurons, and higher brain …

Intramuscular injections of progesterone (P4) are common during assisted reproduction,
which can cause painful injection area reactions, and the current study was therefore …

Obljetnice su prilika za zastati i osvrnuti se oko sebe. Je li 10 godina puno? A 50 godina?
Nije stvar u godinama, već kako smo ih popunili. Na ovim stranicama ćete pronaći tko su bili …

Purinergic P2Y receptors are a family of eight G protein-coupled receptors (P2Y1, 2, 4, 6, 11,
12, 13, 14) that are activated by nucleotides to elicit both vasoconstriction and vasodilation …