Structural diversity, biosynthesis, and biological functions of lipopeptides from Streptomyces

S Zhang, Y Chen, J Zhu, Q Lu, MJ Cryle… - Natural Product …, 2023 - pubs.rsc.org
Covering: up to 2022 Streptomyces are ubiquitous in terrestrial and marine environments,
where they display a fascinating metabolic diversity. As a result, these bacteria are a prolific …

[HTML][HTML] Recent Advances in Marine-Derived Compounds as Potent Antibacterial and Antifungal Agents: A Comprehensive Review

D Bharathi, J Lee - Marine Drugs, 2024 - mdpi.com
The increase in antimicrobial resistance (AMR) in microorganisms is a significant global
health concern. Various factors contribute to AMR, including alterations in cell membrane …

Recent advances in polypeptide antibiotics derived from marine microorganisms

W Wang, L Gu, J Wang, X Hu, B Wei, H Zhang, H Wang… - Marine Drugs, 2023 - mdpi.com
In the post-antibiotic era, the rapid development of antibiotic resistance and the shortage of
available antibiotics are triggering a new health-care crisis. The discovery of novel and …

Targeted isolation of asperheptatides from a coral-derived fungus using LC-MS/MS-based molecular networking and antitubercular activities of modified cinnamate …

R Chao, XM Hou, WF Xu, Y Hai, MY Wei… - Journal of Natural …, 2020 - ACS Publications
Under the guidance of MS/MS-based molecular networking, four new cycloheptapeptides,
namely, asperheptatides A–D (1–4), were isolated together with three known analogues …

Natural products and their analogues acting against Mycobacterium tuberculosis: A recent update

G Kumar - Drug Development Research, 2023 - Wiley Online Library
Tuberculosis (TB) remains one of the deadliest infectious diseases caused by
Mycobacterium tuberculosis (M. tb). It is responsible for significant causes of mortality and …

MGCEP 1.0: A genetic-engineered marine-derived chassis cell for a scaled heterologous expression platform of microbial bioactive metabolites

Z Yang, C Liu, Y Wang, Y Chen, Q Li… - ACS Synthetic …, 2022 - ACS Publications
Marine microorganisms produce a variety of bioactive secondary metabolites, which
represent a significant source of novel antibiotics. Heterologous expression is a valuable …

Microbial-derived peptides with anti-mycobacterial potential

P Zhao, P Hou, Z Zhang, X Li, C Quan, Y Xue… - European Journal of …, 2024 - Elsevier
Tuberculosis (TB), an airborne infectious disease caused by Mycobacterium tuberculosis,
has become the leading cause of death. The subsequent emergence of multidrug-resistant …

The Antitubercular Activities of Natural Products with Fused-Nitrogen-Containing Heterocycles

HI Boshoff, N Malhotra, CE Barry III, S Oh - Pharmaceuticals, 2024 - mdpi.com
Tuberculosis (TB) is notorious as the leading cause of death worldwide due to a single
infectious entity and its causative agent, Mycobacterium tuberculosis (Mtb), has been able to …

Medium-sized peptides from microbial sources with potential for antibacterial drug development

J Chen, W Wang, X Hu, Y Yue, X Lu, C Wang… - Natural Product …, 2024 - pubs.rsc.org
Covering: 1993 to the end of 2022As the rapid development of antibiotic resistance shrinks
the number of clinically available antibiotics, there is an urgent need for novel options to fill …

Cinnamoyl lipids as novel signaling molecules modulate the physiological metabolism of cross-phylum microorganisms

X Liu, Y Li, J Li, J Ren, D Li, S Zhang, Y Wu, J Li… - Communications …, 2024 - nature.com
Signaling systems of microorganisms are responsible for regulating the physiological and
metabolic processes and also play vital roles in the communications of cells. Identifying …