Real-world effectiveness of early molnupiravir or nirmatrelvir–ritonavir in hospitalised patients with COVID-19 without supplemental oxygen requirement on admission …
Background Data on the effectiveness of oral antivirals in patients with mild-to-moderate
COVID-19 are urgently needed. This retrospective cohort study aimed to evaluate the …
COVID-19 are urgently needed. This retrospective cohort study aimed to evaluate the …
Molnupiravir Revisited—Critical Assessment of Studies in Animal Models of COVID-19
HB Rasmussen, PR Hansen - Viruses, 2023 - mdpi.com
Molnupiravir, a prodrug known for its broad antiviral activity, has demonstrated efficacy in
animal models of COVID-19, prompting clinical trials, in which initial results indicated a …
animal models of COVID-19, prompting clinical trials, in which initial results indicated a …
Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir among COVID-19 inpatients during Hong Kong's Omicron BA. 2 wave: an observational study
Background Real-world evidence on the effectiveness of oral antivirals in mild-to-moderate
COVID-19 patients is urgently needed. This retrospective cohort study aims to evaluate the …
COVID-19 patients is urgently needed. This retrospective cohort study aims to evaluate the …
Interferon β-1a ring prophylaxis to reduce household transmission of SARS-CoV-2: a cluster randomised clinical trial
JA Castro-Rodriguez, EN Fish, ST Montgomery… - …, 2023 - thelancet.com
Background Accumulating evidence indicates that an early, robust type 1 interferon (IFN)
response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an …
response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an …
Monitoring antiviral active metabolite (N-hydroxycytidine) levels in plasma in presence of carboxylesterase-2 inhibitor verapamil using copper …
This study focuses on the determination of the active metabolite of molnupiravir (MOL), N-
hydroxycytidine (NHC), using a square wave voltammetric (SWV) method. Carboxylesterase …
hydroxycytidine (NHC), using a square wave voltammetric (SWV) method. Carboxylesterase …
Virus-mediated cell fusion of SARS-CoV-2 variants
A Amidei, HM Dobrovolny - Mathematical Biosciences, 2024 - Elsevier
SARS-CoV-2 has the ability to form large multi-nucleated cells known as syncytia. Little is
known about how syncytia affect the dynamics of the infection or severity of the disease. In …
known about how syncytia affect the dynamics of the infection or severity of the disease. In …
[HTML][HTML] Real-world effectiveness of early molnupiravir and nirmatrelvir/ritonavir among hospitalized, non-oxygen-dependent COVID-19 patients on admission during …
Background Effectiveness of oral antivirals in mild-to-moderate COVID-19 patients is
urgently needed. This retrospective cohort study aims to evaluate the clinical and virologic …
urgently needed. This retrospective cohort study aims to evaluate the clinical and virologic …
What Is New in Prophylaxis and Treatment of COVID-19 in Renal Transplant Patients? A Report from an ESOT Meeting on the Topic
M Salvadori - Transplantology, 2022 - mdpi.com
I should highlight that this manuscript is not a formal review on the topic, but a report from an
ESOT meeting held on 22 June 2022. The assumption of immunosuppressants exposes …
ESOT meeting held on 22 June 2022. The assumption of immunosuppressants exposes …
What is New in Prophylaxis and Treatment of Covid-19 in Renal Transplant Patients?
M Salvadori - 2022 - preprints.org
Kidney transplant recipients, because of a weak immune response due to the assumption of
immunosuppressant are exposed to the risk of COVID-19 infection. This fact realize the …
immunosuppressant are exposed to the risk of COVID-19 infection. This fact realize the …