Alzheimer's disease (AD) brain is characterized by amyloid β-peptide (Aβ) deposits,
neurofibrillary tangles, synapse loss, and extensive oxidative stress. Aβ-induced oxidative …

Alzheimer's disease (AD) is the most common form of dementia in elder people,
characterised by a progressive decline in memory as a result of an impairment of cholinergic …

We have previously synthesized a series of hybrid compounds by linking ferulic acid to
tacrine as multifunctional agents based on the hypotheses that Alzheimer's disease (AD) …

Oxidative damage is associated with neurodegenerative disorders such as Alzheimer's
disease (AD). The antioxidant alpha-lipoic acid has been found to improve memory in …

It has become increasingly apparent that defective insulin signaling may increase the risk for
developing Alzheimer's disease (AD), influence neurodegeneration through promotion of …

Accumulating evidence has suggested the involvement of oxidative stress in the
pathogenesis of Alzheimer's disease (AD). The main endogenous antioxidant, glutathione …

Mitochondrial dysfunction is well recognized as a critical component of the complicated
pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's …

Double-stranded RNAs (dsRNA) serve as viral ligands that trigger innate immunity in
astrocytes and microglial, as mediated through Toll-like receptor 3 (TLR3) and dsRNA …

Obulesu M, Venu R, Somashekhar R. Lipid peroxidation in Alzheimer's Disease: emphasis
on metal‐mediated neurotoxicity. Acta Neurol Scand: 2011: 124: 295–301.© 2011 John …

Superoxide oxidizes epinephrine to a semiquinone, initiating a series of reactions leading to
the colored product adrenochrome. This popular assay for superoxide is more sensitive at …