Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and electroretinography

H Komatsu, G Onoguchi, SM Silverstein, S Jerotic… - Molecular …, 2024 - nature.com
Introduction Abnormal findings on optical coherence tomography (OCT) and
electroretinography (ERG) have been reported in participants with schizophrenia spectrum …

Association between retinal features from multimodal imaging and schizophrenia

SK Wagner, M Cortina-Borja, SM Silverstein… - JAMA …, 2023 - jamanetwork.com
Importance The potential association of schizophrenia with distinct retinal changes is of
clinical interest but has been challenging to investigate because of a lack of sufficiently large …

[HTML][HTML] Association between polygenic risk for schizophrenia and retinal morphology: A cross-sectional analysis of the United Kingdom Biobank

BA Blose, SM Silverstein, KV Stuart, PA Keane… - Psychiatry …, 2024 - Elsevier
We examined the relationship between genetic risk for schizophrenia (SZ), using polygenic
risk scores (PRSs), and retinal morphological alterations. Retinal structural and vascular …

Comparative quantifications and morphological monitoring of the topical treatment approach for onychomycosis-affected in vivo toenail using optical coherence …

SA Saleah, Y Gu, RE Wijesinghe, D Seong… - … Signal Processing and …, 2024 - Elsevier
Onychomycosis is one of the most common toenail fungal infections that affect the quality of
life of many patients. Long-term and noninvasive monitoring of morphological changes of …

Schizophrenia in translation: why the eye?

SM Silverstein, JJ Choi, KM Green… - Schizophrenia …, 2022 - academic.oup.com
Schizophrenia is increasingly recognized as a systemic disease, characterized by
dysregulation in multiple physiological systems (eg, neural, cardiovascular, endocrine) …

Retinal layers and symptoms and inflammation in schizophrenia

MA Carriello, DFB Costa, PHP Alvim… - European Archives of …, 2024 - Springer
Schizophrenia is a neurodevelopmental disorder that affects brain structure and function.
The retina, as well as the brain, consists of neuronal and glial cells packed in layers. Cortical …

[HTML][HTML] Deep retinal layer microvasculature alterations in schizophrenia

SI Fradkin, D Bannai, P Lizano, A Lai, C Crosta… - Biomarkers in …, 2024 - Elsevier
A subset of individuals with schizophrenia (SZ) are thought to have a microvascular
component to their illness with studies demonstrating alterations in retinal superficial, deep …

Oculomics: A Crusade Against the Four Horsemen of Chronic Disease

EJ Patterson, AD Bounds, SK Wagner… - Ophthalmology and …, 2024 - Springer
Chronic, non-communicable diseases present a major barrier to living a long and healthy
life. In many cases, early diagnosis can facilitate prevention, monitoring, and treatment …

Retinal microvasculature in schizophrenia: A meta-analysis with trial sequential analysis of studies assessing vessel density using Optical Coherence Tomography …

SS Janti, SK Tikka - Asian Journal of Psychiatry, 2023 - Elsevier
We performed a series of random-effects meta-analyses on cross-sectional studies
assessing vessel density (VD) using Optical Coherence Tomography Angiography (OCTA) …

[HTML][HTML] Exploring the Neural Effects of Adverse Childhood Experiences Through the Retina

BA Blose - Biomarkers in Neuropsychiatry, 2024 - Elsevier
Adverse childhood experiences (ACEs) are associated with developing systemic diseases
and mental illnesses, affecting multiple body systems, including those that affect allostasis …