Osteoclast precursors, RANKL/RANK, and immunology

L Xing, EM Schwarz, BF Boyce - Immunological reviews, 2005 - Wiley Online Library
Rapid progress has been made in recent years in our understanding of the mechanisms
regulating the formation, activation, and survival of osteoclasts, which are derived from …

Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease

BF Boyce, EM Schwarz, L Xing - Current opinion in rheumatology, 2006 - journals.lww.com
Osteoclast precursors: cytokine-stimulated immunomodulators... : Current Opinion in
Rheumatology Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory …

MCP-1 is induced by receptor activator of nuclear factor-κB ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor …

MS Kim, CJ Day, NA Morrison - Journal of Biological Chemistry, 2005 - ASBMB
Human osteoclast formation from monocyte precursors under the action of receptor activator
of nuclear factor-κB ligand (RANKL) was suppressed by granulocyte macrophage colony …

Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis

MD Cantley, DP Fairlie, PM Bartold, V Marino… - …, 2015 - academic.oup.com
Abstract Objective. Histone deacetylase 1 (HDAC1) is highly expressed in the synovium of
RA patients. Thus we aimed to investigate a novel HDAC inhibitor (HDACi), NW-21 …

Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro

MD Cantley, DP Fairlie, PM Bartold… - Journal of cellular …, 2011 - Wiley Online Library
Histone deacetylase inhibitors (HDACi) suppress cancer cell growth, inflammation, and
bone resorption. The aim of this study was to determine the effect of inhibitors of different …

Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated …

MS Kim, CL Magno, CJ Day… - Journal of cellular …, 2006 - Wiley Online Library
Chemokines MCP‐1 and RANTES are induced when authentic bone resorbing human
osteoclasts differentiate from monocyte precursors in vitro. In addition, MCP‐1 and RANTES …

Sperm sexing in Nili-Ravi buffalo through modified swim up: Validation using SYBR® green real-time PCR

MA Awan, A Mehmood, T Sultana, Q Shahzad… - Animal reproduction …, 2017 - Elsevier
Sperm sexing through flow-sorting technology is relatively expensive, requires considerable
technical support and is actually not practicable in many developing countries. The aim of …

Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro

K Algate, D Haynes, T Fitzsimmons… - Journal of Cellular …, 2020 - Wiley Online Library
The regulation of epigenetic factors is an emerging therapeutic target of immune function in
a variety of osteolytic pathologies. Histone deacetylases (HDAC) modify core histone …

Dominant negative MCP‐1 blocks human osteoclast differentiation

NA Morrison, CJ Day… - Journal of cellular …, 2014 - Wiley Online Library
Human osteoclasts were differentiated using receptor activator of NFκB ligand (RANKL) and
macrophage colony stimulating factor (M‐CSF) from colony forming unit‐granulocyte …

Azithromycin suppresses human osteoclast formation and activity in vitro

SC Gannon, MD Cantley, DR Haynes… - Journal of Cellular …, 2013 - Wiley Online Library
Azithromycin is an antibiotic with anti‐inflammatory properties used as an adjunct to treat
periodontitis, a common inflammatory mediated condition featuring pathologic alveolar bone …