Global colistin use: a review of the emergence of resistant Enterobacterales and the impact on their genetic basis

U Binsker, A Käsbohrer… - FEMS Microbiology …, 2022 - academic.oup.com
The dramatic global rise of MDR and XDR Enterobacterales in human medicine forced
clinicians to the reintroduction of colistin as last-resort drug. Meanwhile, colistin is used in …

Antibiotic heteroresistance in Klebsiella pneumoniae: definition, detection methods, mechanisms, and combination therapy

JY Lin, ZC Zhu, J Zhu, L Chen, H Du - Microbiological Research, 2024 - Elsevier
Klebsiella pneumoniae is a common opportunistic pathogen that presents significant
challenges in the treatment of infections due to its resistance to multiple antibiotics. In recent …

Challenges and opportunities of phage therapy for Klebsiella pneumoniae infections

X Kou, X Yang, R Zheng - Applied and Environmental …, 2024 - journals.asm.org
Traditional antibiotics have been effective in many cases. However, the rise in multidrug-
resistant bacteria has diminished their therapeutic efficacy, signaling the dawn of an era …

Antimicrobial peptides against polymyxin-resistant Klebsiella pneumoniae: a patent review

GHA de Souza, L Rossato, AR de Oliveira… - World Journal of …, 2023 - Springer
The spread of polymyxin-resistant Klebsiella pneumoniae strains represents an emerging
health challenge, limiting treatment options for the patients. Thus, the development of new …

Prolonged Outbreak of Carbapenem and Colistin-Resistant Klebsiella pneumoniae at a Large Tertiary Hospital in Brazil

VFD Rocha, MS Barbosa, HF Leal, GEO Silva… - Frontiers in …, 2022 - frontiersin.org
Multidrug-resistant gram-negative bacteria, such as carbapenem and colistin-resistant
Klebsiella pneumoniae (ColR-CRKP), represent a major problem for health systems …

[HTML][HTML] Nanostructures for Delivery of Flavonoids with Antibacterial Potential against Klebsiella pneumoniae

HLRQ Macêdo, LL de Oliveira, DN de Oliveira… - Antibiotics, 2024 - mdpi.com
Flavonoids are secondary metabolites that exhibit remarkable biological activities, including
antimicrobial properties against Klebsiella pneumoniae, a pathogen responsible for several …

Extended-Spectrum Beta-Lactamase-Producing Escherichia coli and Other Antimicrobial-Resistant Gram-Negative Pathogens Isolated from Bovine Mastitis: A One …

BL Nery Garcia, STA Dantas, K da Silva Barbosa… - Antibiotics, 2024 - mdpi.com
Antimicrobial resistance (AMR) poses an imminent threat to global public health, driven in
part by the widespread use of antimicrobials in both humans and animals. Within the dairy …

First report of ISKpn26 element mediating mgrB gene disruption in the ST1 colistin- and carbapenem-resistant Klebsiella pneumoniae cluster isolated from a patient …

X Li, S Shen, Y Feng, H Shen, F Hu… - Microbiology Spectrum, 2024 - journals.asm.org
Colistin is used as a last-line therapy against carbapenem-resistant Klebsiella pneumoniae
(CRKP). However, colistin resistance in Klebsiella pneumoniae is increasingly reported …

[HTML][HTML] Phenotypic and molecular characterization of multi-drug resistant Klebsiella spp. isolates recovered from clinical settings

H Diab, K Rahy, T Jisr, M El Chaar, E Abboud… - Infection, Genetics and …, 2024 - Elsevier
Klebsiella pneumoniae is a Gram-negative bacterium that colonizes the gastrointestinal tract
and nasopharynx with many being linked to nosocomial infections. Extended-spectrum β …

临床感染标本的病原菌分布及耐药性分析

陈科, 樊菲菲 - 临床急诊杂志, 2021 - lcjz.whuhzzs.com
目的: 获取我院急诊重症监护室(EICU) 5 年来病原菌分布和耐药状况的流行病学资料,
为临床合理使用抗菌药物和经验治疗提供依据. 方法: 收集2016 年1 月—2020 年12 …