A domino reaction has been defined by Tietze as a reaction involving two or more bond-
forming transformations that take place under the same reaction conditions, without adding …

The prevalence of nitrogen containing heterocycles in natural products and pharmaceuticals
is a doubtless fact. In this review, recent applications of a stereoselective aza-Michael …

1, 2, 3, 4-Tetrahydro-β-carbolines (THβCs) are a pharmacologically important group of
compounds belonging to the indole alkaloids. C1-Substituted optically active THβCs have …

A new approach for the facile synthesis of fused quinazolinone scaffolds through a
palladium‐catalyzed carbonylative coupling followed by an intramolecular nucleophilic …

Multicomponent reactions, especially those involving four or even more reagents, have been
a long‐standing challenge because of the issues associated with balancing reactivity …

Given the importance of quinazolinones and carbonylative transformations, a palladium‐
catalyzed four‐component carbonylative coupling system for the synthesis of diverse 4 (3H) …

A novel, four-component synthetic strategy to synthesize a series of β-difluoroalkyl
unsaturated esters/amides with high regioslectivity is described. This Pd-catalyzed …

A palladium-catalyzed domino cyclization and carboxylation reaction for synthesis of a
variety of carboxylic acids was developed, where chloroform was used as “carbon …

In this study, palladium‐catalyzed domino Heck–Sonogashira reactions have been
developed in water. Using this strategy, a series of 3‐(4‐aminobut‐2‐ynyl) oxindole …

Reported here are methods for the direct construction of a range of spirocyclized oxindoles
and indolenines in good to excellent yields. Specifically, we report the palladium-catalyzed …