The ancient two-faced Roman god Janus is often used as a metaphor to describe the
characteristics of the Glucocorticoid Receptor (NR3C1), which exhibits both a beneficial …

The hypothalamic-pituitary-adrenal (HPA) axis maintains basal and stress-related
homeostasis in vertebrates. Skin expresses all elements of the HPA axis including …

Consuming protein following exercise has been shown to stimulate protein synthesis acutely
in skeletal muscle and has been recommended to prevent sarcopenia. It is not known …

Glucocorticoid hormones exert crucial effects on the brain in relation to physiology,
endocrine regulation, mood and cognition. Their two receptor types, glucocorticoid and …

Background Delayed wound healing or infection leads to premature tissue expander (TE)
explantation after immediate postmastectomy breast reconstruction. A large study with …

Glucocorticoids contribute to adipocyte differentiation by cooperating with transcription
factors, such as CCAAT/enhancer-binding protein β (C/EBPβ), to stimulate transcription of …

Background: An acellular dermal matrix will typically incorporate, in time, with the overlying
mastectomy skin flap. This remodeling process may be adversely impacted in patients who …

Glucocorticoids are extremely effective anti-inflammatory therapies, but their clinical use is
limited due to severe side effects, including osteoporosis, muscle wasting, fat redistribution …

Objective The study purpose was to evaluate the associations between patient
characteristics and the histologic remodeling scores of acellular dermal matrices (ADMs) …

Glyceroneogenesis is important for the maintenance of fat content in white adipose tissue
(WAT). An increase in WAT, and especially the pattern of fat distribution, specifically in …