Hepcidin-ferroportin interaction controls systemic iron homeostasis
Despite its abundance in the environment, iron is poorly bioavailable and subject to strict
conservation and internal recycling by most organisms. In vertebrates, the stability of iron …
conservation and internal recycling by most organisms. In vertebrates, the stability of iron …
[HTML][HTML] Iron metabolism and iron disorders revisited in the hepcidin era
C Camaschella, A Nai, L Silvestri - Haematologica, 2020 - ncbi.nlm.nih.gov
Iron is biologically essential, but also potentially toxic; as such it is tightly controlled at cell
and systemic levels to prevent both deficiency and overload. Iron regulatory proteins post …
and systemic levels to prevent both deficiency and overload. Iron regulatory proteins post …
Iron deficiency
C Camaschella - Blood, The Journal of the American Society of …, 2019 - ashpublications.org
Abstract Iron deficiency anemia affects> 1.2 billions individuals worldwide, and iron
deficiency in the absence of anemia is even more frequent. Total-body (absolute) iron …
deficiency in the absence of anemia is even more frequent. Total-body (absolute) iron …
Transferrin and transferrin receptors update
H Kawabata - Free Radical Biology and Medicine, 2019 - Elsevier
In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is
incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular …
incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular …
[HTML][HTML] The role of vitamins and minerals in hair loss: a review
HM Almohanna, AA Ahmed, JP Tsatalis… - Dermatology and therapy, 2019 - Springer
People commonly inquire about vitamin and mineral supplementation and diet as a means
to prevent or manage dermatological diseases and, in particular, hair loss. Answering these …
to prevent or manage dermatological diseases and, in particular, hair loss. Answering these …
Iron-deficiency anemia
C Camaschella - New England journal of medicine, 2015 - Mass Medical Soc
Iron-Deficiency Anemia | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Overview of iron metabolism in health and disease
Iron is an essential element for numerous fundamental biologic processes, but excess iron is
toxic. Abnormalities in systemic iron balance are common in patients with chronic kidney …
toxic. Abnormalities in systemic iron balance are common in patients with chronic kidney …
The multifaceted role of iron in renal health and disease
RPL van Swelm, JFM Wetzels… - Nature Reviews …, 2020 - nature.com
Iron is an essential element that is indispensable for life. The delicate physiological body
iron balance is maintained by both systemic and cellular regulatory mechanisms. The iron …
iron balance is maintained by both systemic and cellular regulatory mechanisms. The iron …
Liver iron sensing and body iron homeostasis
The liver orchestrates systemic iron balance by producing and secreting hepcidin. Known as
the iron hormone, hepcidin induces degradation of the iron exporter ferroportin to control …
the iron hormone, hepcidin induces degradation of the iron exporter ferroportin to control …
[HTML][HTML] Regulation of the iron homeostatic hormone hepcidin
V Sangkhae, E Nemeth - Advances in nutrition, 2017 - Elsevier
Iron is required for many biological processes but is also toxic in excess; thus, body iron
balance is maintained through sophisticated regulatory mechanisms. The lack of a regulated …
balance is maintained through sophisticated regulatory mechanisms. The lack of a regulated …