Critical review on the presence of phthalates in food and evidence of their biological impact

A Giuliani, M Zuccarini, A Cichelli, H Khan… - International journal of …, 2020 - mdpi.com
Phthalates are a huge class of chemicals with a wide spectrum of industrial uses, from the
manufacture of plastics to food contact applications, children's toys, and medical devices …

Endocrine disrupting chemicals: Impacts on human fertility and fecundity during the peri-conception period

MP Green, AJ Harvey, BJ Finger, GA Tarulli - Environmental research, 2021 - Elsevier
It is becoming increasingly difficult to avoid exposure to man-made endocrine disrupting
chemicals (EDCs) and environmental toxicants. This escalating yet constant exposure is …

Di-(2-ethylhexyl) phthalate exposure leads to ferroptosis via the HIF-1α/HO-1 signaling pathway in mouse testes

Y Wu, J Wang, T Zhao, J Chen, L Kang, Y Wei… - Journal of hazardous …, 2022 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is an extensively used plasticizer and has been
shown to cause reproductive dysfunction in humans and model animals. However, the exact …

Associations between urinary phthalate metabolite concentrations and rheumatoid arthritis in the US adult population

Y Chen, J Shen, Y Wu, L Fang, S Xu, Y Peng, F Pan - Chemosphere, 2023 - Elsevier
Phthalates are ubiquitous environmental contaminants. Nevertheless, limited data is
available about the impacts of phthalates on rheumatoid arthritis (RA). The purpose of this …

Mechanisms of testicular disruption from exposure to bisphenol A and phtalates

F Pallotti, M Pelloni, D Gianfrilli, A Lenzi… - Journal of Clinical …, 2020 - mdpi.com
Great attention has been paid in recent years to the harmful effects of various chemicals that
interfere with our natural hormone balance, collectively known as endocrine-disrupting …

[HTML][HTML] Seminal plasma metabolome in relation to semen quality and urinary phthalate metabolites among Chinese adult men

YX Wang, Y Wu, HG Chen, P Duan, L Wang… - Environment …, 2019 - Elsevier
Background A growing body of evidence has found links between endocrine disruptor
phthalates and male reproductive disorders, but the mechanisms underlying these …

Associations of environmental phthalate exposure with male steroid hormone synthesis and metabolism: an integrated epidemiology and toxicology study

M Tian, S Wu, YX Wang, L Liu, J Zhang, H Shen… - Journal of Hazardous …, 2022 - Elsevier
Humans are simultaneously and constantly exposed to various lipophilic chain phthalate
acid esters. The association of urinary phthalate metabolites with altered male steroid …

[HTML][HTML] Applying hair exposome for linking environmental exposure to reproductive health: A comprehensive review and research perspective

M Ren, M Fang, J Liu, Q Lu, H Bao, L Zhuang… - Hygiene and …, 2024 - Elsevier
Increasing evidences have revealed a close relationship between various environmental
exposures and reproductive health. The real-world complex exposure scenario along with …

Positive association of low-level environmental phthalate exposure with sperm motility was mediated by DNA methylation: a pilot study

M Tian, L Liu, J Zhang, Q Huang, H Shen - Chemosphere, 2019 - Elsevier
Accumulating evidence indicates that phthalate exposures may affect human semen quality.
Epigenetic modifications such as DNA methylation might be linked chemical exposure and …

Water and soil pollution as determinant of water and food quality/contamination and its impact on male fertility

A Di Nisio, C Foresta - Reproductive biology and endocrinology, 2019 - Springer
Over the past two decades, public health has focused on the identification of environmental
chemical factors that are able to adversely affect hormonal function, known as endocrine …