IgG glycosylation is currently at the forefront of both immunology and glycobiology, likely due in part to the widespread and growing use of antibodies as drugs. For over four decades, it …
Rationale: One measure of protein glycosylation (GlycA) has been reported to predict higher cardiovascular risk by reflecting inflammatory pathways. Objective: The main objective of this …
N-glycosylation is a frequent modification of proteins, essential for all domains of life. N- glycan biosynthesis is a dynamic, complex, non-templated process, wherein specific …
Immunoglobulin G (IgG) antibodies are post-translationally modified by the addition of complex carbohydrate molecules–glycans, which have profound effects on the IgG function …
Antibodies are known to have an important role in the development of rheumatoid arthritis (RA), one of the most prevalent chronic inflammatory diseases which primarily involves the …
Background Chronic obstructive pulmonary disease (COPD) is a complex condition, whose diagnosis requires spirometric assessment. However, considering its heterogeneity …
Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels. IgG glycome composition …
Highlights•Nanosponges are explored for their antiviral delivery and biological neutralization potentials.•Cellular nanosponges block interactions between SARS-CoV-2 …
ABSTRACT DNA methylation (DNAm) is one of the most studied epigenetic modifications. DNAm has emerged as a key biological mechanism and biomarkers to test associations …