In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

Exopolysaccharide is a key part of the extracellular matrix that contributes to important
mechanisms of bacterial pathogenicity, most notably biofilm formation and immune evasion …

Replication-transcription collisions shape genomes, influence evolution, and promote
genetic diseases. Although unclear why, head-on transcription (lagging strand genes) is …

Nearly all bacterial species, including pathogens, have the ability to form biofilms. Biofilms
are defined as structured ecosystems in which microbes are attached to surfaces and …

The conserved RNA-binding protein ProQ has emerged as the centerpiece of a previously
unknown third large network of post-transcriptional control in enterobacteria. Here, we have …

Highlights•3′ regions of bacterial mRNAs are emerging as a rich source of regulatory
sRNAs.•Two major types of sRNA biogenesis from mRNA 3′ regions.•sRNAs from mRNA …

Abstract Treatment of methicillin-resistant Staphylococcus aureus infections is dependent on
the efficacy of last-line antibiotics including vancomycin. Treatment failure is commonly …

Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes …

Staphylococcus aureus is a leading cause of both community-and hospital-acquired
infections that are increasingly antibiotic resistant. The emergence of S. aureus resistance to …