Materials for oral delivery of proteins and peptides

TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …

[HTML][HTML] Electrospinning technologies for the delivery of Biopharmaceuticals: Current status and future trends

S Lian, D Lamprou, M Zhao - International Journal of Pharmaceutics, 2024 - Elsevier
This review provides an in-depth exploration of electrospinning techniques employed to
produce micro-or nanofibres of biopharmaceuticals using polymeric solutions or melts with …

Electrospinning: A novel nano-encapsulation approach for bioactive compounds

P Wen, MH Zong, RJ Linhardt, K Feng, H Wu - Trends in Food Science & …, 2017 - Elsevier
Background Bioactive compounds have gained increasing attention for their health benefits.
However, the instability of bioactive compounds during food processing and storage, and …

Electrospinning of food proteins and polysaccharides

AC Mendes, K Stephansen, IS Chronakis - Food Hydrocolloids, 2017 - Elsevier
Nano-microfibrous structures of biopolymers with a wide range of compositions,
morphologies, mechanical properties and bioactivities could be developed using …

Electrospun nanofibers as carriers of microorganisms, stem cells, proteins, and nucleic acids in therapeutic and other applications

S Stojanov, A Berlec - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
Electrospinning is a technique that uses polymer solutions and strong electric fields to
produce nano-sized fibers that have wide-ranging applications. We present here an …

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery

JA Finbloom, F Sousa, MM Stevens… - Advanced drug delivery …, 2020 - Elsevier
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …

Protein encapsulation by electrospinning and electrospraying

A Moreira, D Lawson, L Onyekuru… - Journal of controlled …, 2021 - Elsevier
Given the increasing interest in the use of peptide-and protein-based agents in therapeutic
strategies, it is fundamental to develop delivery systems capable of preserving the biological …

Encapsulation of bioactive compound in electrospun fibers and its potential application

P Wen, Y Wen, MH Zong, RJ Linhardt… - Journal of agricultural …, 2017 - ACS Publications
Electrospinning is a simple and versatile encapsulation technology. Since electrospinning
does not involve severe conditions of temperature or pressure or the use of harsh chemicals …

Electrospinning and electrospraying technologies for food applications

LT Lim, AC Mendes, IS Chronakis - Advances in food and nutrition …, 2019 - Elsevier
Electrospinning and electrospraying are versatile techniques for the production of nano-to
micro-scale fibers and particles. Over the past 2 decades, significant progresses have been …

Nano and microscale delivery platforms for enhanced oral peptide/protein bioavailability

T Tong, L Wang, X You, J Wu - Biomaterials science, 2020 - pubs.rsc.org
In recent years, peptide/protein drugs have attracted considerable attention owing to their
superior targeting and therapeutic effect and fewer side effects compared with chemical …