Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

J Xie, Y Wang, W Choi, P Jangili, Y Ge, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Stimuli-responsive switchable MRI nanoprobe for tumor theranostics

B Chen, L Liu, R Yue, Z Dong, C Lu, C Zhang, G Guan… - Nano Today, 2023 - Elsevier
With the advancement in magnetic resonance imaging (MRI) technology, traditional single T
1 or T 2 contrast agents struggle to meet the demend for accuracy imaging. In comparison …

Mixed‐metal MOF‐derived hollow porous nanocomposite for trimodality imaging guided reactive oxygen species‐augmented synergistic therapy

Y Cheng, C Wen, YQ Sun, H Yu… - Advanced Functional …, 2021 - Wiley Online Library
Here an excellent trimodality imaging‐guided synergistic photothermal therapy
(PTT)/photodynamic therapy (PDT)/chemodynamic therapy (CDT) is proposed. To this end …

Platinum Crosslinked Carbon Dot@TiO2−x p‐n Junctions for Relapse‐Free Sonodynamic Tumor Eradication via High‐Yield ROS and GSH Depletion

B Geng, S Xu, P Li, X Li, F Fang, D Pan, L Shen - Small, 2022 - Wiley Online Library
Sonodynamic therapy as a promising noninvasive modality is being developed for tumor
therapy, but there is a lack of next‐generation sonosensitizers that can generate full ROS at …

[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review

A Doustmihan, M Fathi, MA Mazloomi, A Salemi… - Journal of Controlled …, 2023 - Elsevier
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …

Neisseria meningitidis Opca Protein/MnO2 Hybrid Nanoparticles for Overcoming the Blood–Brain Barrier to Treat Glioblastoma

CY Dong, QX Huang, H Cheng, DW Zheng… - Advanced …, 2022 - Wiley Online Library
The major hurdle in glioblastoma therapy is the low efficacy of drugs crossing the blood–
brain barrier (BBB). Neisseria meningitidis is known to specifically enrich in the central …

Nanoarchitectured manganese dioxide (MnO2)-based assemblies for biomedicine

HY Xia, BY Li, Y Zhao, YH Han, SB Wang… - Coordination Chemistry …, 2022 - Elsevier
The transition elements (groups IIIB to IIB)-based materials present advantageous
morphological and physicochemical attributes due to the exceptionally variable valence …

H2O2-Responsive Gold Nanoclusters @ Mesoporous Silica @ Manganese Dioxide Nanozyme for “Off/On” Modulation and Enhancement of Magnetic Resonance …

Z Yin, Q Ji, D Wu, Z Li, M Fan, H Zhang… - … applied materials & …, 2021 - ACS Publications
In order to achieve safe and high-efficient photodynamic therapy (PDT), it was a powerful
strategy of constructing O2-generated nanozyme with intelligent “off/on” modulation and …

Tumor‐Microenvironment‐Triggered Ion Exchange of a Metal–Organic Framework Hybrid for Multimodal Imaging and Synergistic Therapy of Tumors

Y Chen, ZH Li, P Pan, JJ Hu, SX Cheng… - Advanced …, 2020 - Wiley Online Library
Nanotheranostic agents (NTAs) that integrate diagnostic capabilities and therapeutic
functions have great potential for personalized medicine, yet poor tumor specificity severely …

[HTML][HTML] Efficacy-shaping nanomedicine by loading calcium peroxide into tumor microenvironment-responsive nanoparticles for the antitumor therapy of prostate …

D Wu, ZQ Zhu, HX Tang, ZE Shi, J Kang, Q Liu, J Qi - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Prostate cancer has become one of the most threatening malignant tumors in
men, leading to an imperative need to develop effective and safe therapies. Because of the …