The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

A variety of in vivo experimental models have been established for the studies of human
cancer using both cancer cell lines and patient-derived xenografts (PDXs). In order to meet …

Cervical cancer is one of the most common cancers affecting women worldwide. There are
an estimated 570.000 new cases of cervical cancer each year and conventional treatments …

The establishment of clinically relevant models for tumor metastasis and drug testing is a
major challenge in cancer research. Here we report a physiologically relevant assay …

Survival rates of osteosarcoma patients could not be significantly improved by conventional
chemotherapeutic treatment regimens since the introduction of high-dose chemotherapy 35 …

Introduction: Advancements in cancer management and treatment are associated with
strong preclinical research data, in which reliable cancer models are demanded. Indeed …

In the last decade, the chicken chorioallantoic membrane (CAM) assay has been re-
discovered in cancer research to study the molecular mechanisms of anti-cancer drug …

Neuroblastoma is a paediatric cancer of the sympathetic nervous system and the most
common solid tumour of infancy, contributing to 15% of paediatric oncology deaths. Current …

Cancer stem cells (CSCs) residing in colorectal cancer tissues have tumorigenic capacity
and contribute to chemotherapeutic resistance and disease relapse. It is well known that the …

Simple Summary Circulating cancer cells—and in particular their very rare subpopulation,
circulating cancer stem cells (cCSCs)—are responsible for recurrence and metastasis. In …