The design of small complexes that bind and react at specific sequences of DNA becomes
important as we begin to delineate, on a molecular level, how genetic information is …

This review will cover the developments in the chemistry of phenanthroline-based ligands in
the last 10–15 years. 1, 10-Phenanthroline (phen) is a classic ligand in coordination …

Binding and spectroscopic parameters for a series of mixed-ligand complexes on binding to
DNA have been determined. The application of mixed-ligand complexes permits the …

Ru (phen) 32+ bound to double-helical DNA displays an increase in luminescence owing to
intercalation; emission from the met-al-to-ligand charge transfer (MLCT) excited state decays …

The well-developed synthetic chemistry of ruthenium, particularly with ammine, amine and
imine ligands, provides for many approaches to innovative new metallopharmaceuticals …

Revised Manuscript Received December 28, 1992 abstract: Absorbance and fluorescence
methods, circular dichroism, UV melting experiments, viscosity, and competition dialysis …

Considerable attention has focused on new DNA-binding and-modifying agents, from
natural products to wholly synthetic designs, as probes of DNA structure and as po-tential …

This book covers material that could be included in a one-quarter or one-semester course in
bioinorganic chemistry for graduate students and advanced undergraduate students in …

Rapid photoinduced electron transfer is demonstrated over a distance of greater than 40
angstroms between metallointercalators that are tethered to the 5′ termini of a 15-base pair …

Since the elucidation of the structure of double helical DNA, the construction of small
molecules that recognize and react at specific DNA sites has been an area of considerable …