COVID-19, myocarditis and pericarditis

DL Fairweather, DJ Beetler, DN Di Florio… - Circulation …, 2023 - Am Heart Assoc
Viral infections are a leading cause of myocarditis and pericarditis worldwide, conditions that
frequently coexist. Myocarditis and pericarditis were some of the early comorbidities …

Autoimmune myocarditis, old dogs and new tricks

T Won, EJ Song, HM Kalinoski, JJ Moslehi… - Circulation …, 2024 - Am Heart Assoc
Autoimmunity significantly contributes to the pathogenesis of myocarditis, underscored by its
increased frequency in autoimmune diseases such as systemic lupus erythematosus and …

[HTML][HTML] Sex and Gender Differences in the Pathogenesis and Treatment of Diseases

M Farrokhi, F Taheri, A Moeini, M Farrokhi, S Rabiei… - Kindle, 2023 - preferpub.org
Sex and gender differences play a significant role in the pathogenesis, clinical presentation,
and treatment outcomes of various diseases. These differences arise from a complex …

[HTML][HTML] The SARS-CoV-2 Spike protein induces long-term transcriptional perturbations of mitochondrial metabolic genes, causes cardiac fibrosis, and reduces …

X Cao, V Nguyen, J Tsai, C Gao, Y Tian, Y Zhang… - Molecular …, 2023 - Elsevier
Background As the pandemic evolves, post-acute sequelae of CoV-2 (PASC) including
cardiovascular manifestations have emerged as a new health threat. This study aims to …

Determinants of COVID-19 vaccine-induced myocarditis

J Rose, N Hulscher… - Therapeutic Advances in …, 2024 - journals.sagepub.com
Background: Following the roll-out of the Pfizer-BioNTech BNT162b2, Moderna mRNA-
1273, and Janssen Ad26. COV2. S coronavirus disease 2019 (COVID-19) injections in the …

Reconstituted extracellular vesicles from human platelets decrease viral myocarditis in mice

DJ Beetler, KA Bruno, MM Watkins, V Xu, I Chekuri… - Small, 2023 - Wiley Online Library
Patients with viral myocarditis are at risk of sudden death and may progress to dilated
cardiomyopathy (DCM). Currently, no disease‐specific therapies exist to treat viral …

[HTML][HTML] Mitochondrial extracellular vesicles, autoimmunity and myocarditis

DN Di Florio, DJ Beetler, EJ McCabe, J Sin… - Frontiers in …, 2024 - frontiersin.org
For many decades viral infections have been suspected as 'triggers' of autoimmune disease,
but mechanisms for how this could occur have been difficult to establish. Recent studies …

Sex-and gender-related disparities in chest pain syndromes: The feminine mystique of chest pain

F Angeli, F Ricci, F Moscucci, S Sciomer… - Current Problems in …, 2024 - Elsevier
Chest pain syndromes encompass a wide range of different clinical conditions, being
coronary artery disease one of the most important and feared aetiology. Sex and gender …

[HTML][HTML] The natural history of CVB3 myocarditis in C57BL/6J mice: an extended in-depth characterization

K Favere, M Van Hecke, S Eens, M Bosman… - Cardiovascular …, 2024 - Elsevier
Background and aims Viral infections are the leading cause of myocarditis. Besides acute
cardiac complications, late-stage sequelae such as myocardial fibrosis may develop …

Sex-based differences in late gadolinium enhancement among patients with acute myocarditis

R Cau, F Pisu, JS Suri, R Montisci, G Bastarrika… - European Journal of …, 2023 - Elsevier
Objective The aims of our study were to investigate the sex differences in late gadolinium
enhancement (LGE) using cardiovascular magnetic resonance (CMR) in a single-centre …