[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Enhancing precision in human neuroscience

S Nebe, M Reutter, DH Baker, J Bölte, G Domes… - Elife, 2023 - elifesciences.org
Human neuroscience has always been pushing the boundary of what is measurable. During
the last decade, concerns about statistical power and replicability–in science in general, but …

Navigating the garden of forking paths for data exclusions in fear conditioning research

TB Lonsdorf, M Klingelhöfer-Jens, M Andreatta… - Elife, 2019 - elifesciences.org
In this report, we illustrate the considerable impact of researcher degrees of freedom with
respect to exclusion of participants in paradigms with a learning element. We illustrate this …

[HTML][HTML] Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning

J Haaker, S Maren, M Andreatta, CJ Merz… - Neuroscience & …, 2019 - Elsevier
Translational neuroscience bridges insights from specific mechanisms in rodents to complex
functions in humans and is key to advance our general understanding of central nervous …

Measuring learning in human classical threat conditioning: Translational, cognitive and methodological considerations

KE Ojala, DR Bach - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Threat conditioning is a laboratory model of associative learning across species that is often
used in research on the etiology and treatment of anxiety disorders. At least 10 different …

Pupil dilation as an index of Pavlovian conditioning. A systematic review and meta-analysis

JB Finke, K Roesmann, T Stalder, T Klucken - … & Biobehavioral Reviews, 2021 - Elsevier
The use of pupillometry to track emotional learning processes in humans is generating an
increasing interest. Here, we provide a first systematic review and meta-analysis on the …

[HTML][HTML] I doubt it is safe: A meta-analysis of self-reported intolerance of uncertainty and threat extinction training

J Morriss, S Wake, C Elizabeth… - … Psychiatry Global Open …, 2021 - Elsevier
Background Intolerance of uncertainty (IU), the tendency to find uncertainty distressing, is an
important transdiagnostic dimension in mental health disorders. Higher self-reported IU has …

Measuring the conditioned response: A comparison of pupillometry, skin conductance, and startle electromyography

L Leuchs, M Schneider, VI Spoormaker - Psychophysiology, 2019 - Wiley Online Library
In human fear conditioning studies, different physiological readouts can be used to track
conditioned responding during fear learning. Commonly employed readouts such as skin …

Consensus design of a calibration experiment for human fear conditioning

DR Bach, J Sporrer, R Abend, T Beckers… - Neuroscience & …, 2023 - Elsevier
Fear conditioning is a widely used laboratory model to investigate learning, memory, and
psychopathology across species. The quantification of learning in this paradigm is …

The neurofunctional basis of affective startle modulation in humans: evidence from combined facial electromyography and functional magnetic resonance imaging

M Kuhn, J Wendt, R Sjouwerman, C Büchel, A Hamm… - Biological …, 2020 - Elsevier
Background The startle eye-blink is the cross-species translational tool to study defensive
behavior in affective neuroscience with relevance to a broad range of neuropsychiatric …