Tobacco smoke carcinogens and lung cancer

SS Hecht - Journal of the national cancer institute, 1999 - academic.oup.com
The complexity of tobacco smoke leads to some confusion about the mechanisms by which
it causes lung cancer. Among the multiple components of tobacco smoke, 20 carcinogens …

Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons

A Ramesh, SA Walker, DB Hood… - … journal of toxicology, 2004 - journals.sagepub.com
Polycyclic aromatic hydrocarbons (PAHs) are a family of toxicants that are ubiquitous in the
environment. These contaminants generate considerable interest, because some of them …

Assessment of intake from the diet

R Kroes, D Müller, J Lambe, MRH Löwik… - Food and Chemical …, 2002 - Elsevier
Exposure assessment is one of the key parts of the risk assessment process. Only intake of
toxicologically significant amounts can lead to adverse health effects even for a relatively …

Human urinary carcinogen metabolites: biomarkers for investigating tobacco and cancer

SS Hecht - Carcinogenesis, 2002 - academic.oup.com
Measurement of human urinary carcinogen metabolites is a practical approach for obtaining
important information about tobacco and cancer. This review presents currently available …

Biomonitoring of polycyclic aromatic hydrocarbons in human urine

J Jacob, A Seidel - Journal of Chromatography B, 2002 - Elsevier
Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the
method of choice to determine occupational and/or environmental exposure of an individual …

Tobacco smoke carcinogens and breast cancer

SS Hecht - Environmental and molecular mutagenesis, 2002 - Wiley Online Library
Cigarette smoking is an established cause of a variety of cancer types, but its role in breast
cancer etiology is not clear. In this report, the potential role of cigarette smoke carcinogens …

Biomarkers of exposure to polycyclic aromatic hydrocarbons from environmental air pollution

G Castano-Vinyals, A D'errico, N Malats… - Occupational and …, 2004 - oem.bmj.com
Metabolites of pyrene and DNA adducts have been used as biomarkers of high level
exposure to polycyclic aromatic hydrocarbons (PAHs). A systematic review was performed to …

Biomonitoring of exposure to polycyclic aromatic hydrocarbons of nonoccupationally exposed persons

G Scherer, S Frank, K Riedel, I Meger-Kossien… - … Biomarkers & Prevention, 2000 - AACR
In a field study with 69 subjects, we investigated the influence of smoking, exposure to
environmental tobacco smoke (ETS), diet, and location of residence on biomarkers for …

Relationship between machine-derived smoke yields and biomarkers in cigarette smokers in Germany

G Scherer, J Engl, M Urban, G Gilch, D Janket… - Regulatory toxicology …, 2007 - Elsevier
In order to determine whether smokers of cigarettes in the contemporary yield ranges of the
German market (0.1–1.0 mg nicotine, 1–10mg tar) differ in their actual exposure to various …

Indoor exposure to polycyclic aromatic hydrocarbons and carbon monoxide in traditional houses in Burundi

C Viau, G Hakizimana, M Bouchard - International archives of …, 2000 - Springer
Objectives: Wood combustion is used as a major energy source in African countries and
could result in indoor, pollution-related health problems. This exploratory study was …