Leishmaniasis is endemic to the tropical and subtropical regions of the world and is
transmitted by the bite of an infected sand fly. The multifaceted interactions between …

Leishmaniasis is a neglected infectious disease with clinical presentations ranging from
asymptomatic or mild symptoms to chronic infection and eventual death. The mechanisms of …

Cutaneous leishmaniasis (CL) is a curable disease; however, due to various risk factors,
unresponsiveness to CL treatments is inevitable. The treatment of CL has been firmly …

This study aimed to investigate the in vitro and in silico antileishmanial activity of azacitidine
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …

Leishmaniasis represents a major health concern worldwide which has no effective
treatment modality. Nicotinamide (NAm) has been used for a wide range of applications from …

Leishmaniasis is a disease of poverty that imposes a devastating medical, social, and
economic burden on over 1 billion people nationwide. To date, no in-depth study to analyze …

Toll-like receptors (TLRs) are important for the host immune response to a variety of
pathogens, including bacteria, viruses, fungi, and parasites. These receptors become …

Purpose The aim of this study was to explore the activity of Naja naja oxiana venom on
Leishmania tropica and its modes of action. Methods Different fractions of Naja naja oxiana …

Introduction: Trichomoniasis is the most common non-viral sexually transmitted infection that
increases the risk of cervical cancer. Trichomonas vaginalis (T. vaginalis) can regulate the …

Recombinant live delivery system based on chemokine IFN-γ-inducible protein-10 kDa
(CXCL 10 or IP-10), as a suitable immunotherapy tool, have been used for the treatment of …