Acute otitis media pneumococcal disease burden and nasopharyngeal colonization in children due to serotypes included and not included in current and new …

M Pichichero, R Malley, R Kaur, R Zagursky… - Expert review of …, 2023 - Taylor & Francis
Introduction Despite the introduction of effective pneumococcal conjugate vaccines (PCV),
Streptococcus pneumoniae remains a major cause of acute otitis media (AOM) worldwide …

Otitis media: recent advances in otitis media vaccine development and model systems

A Zahid, JC Wilson, ID Grice, IR Peak - Frontiers in Microbiology, 2024 - frontiersin.org
Otitis media is an inflammatory disorder of the middle ear caused by airways-associated
bacterial or viral infections. It is one of the most common childhood infections as globally …

A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera

R Lappan, K Imbrogno, C Sikazwe, D Anderson… - BMC microbiology, 2018 - Springer
Background Recurrent acute otitis media (rAOM, recurrent ear infection) is a common
childhood disease caused by bacteria termed otopathogens, for which current treatments …

Emerging Streptococcus pneumoniae strains colonizing the nasopharynx in children after 13-valent pneumococcal conjugate vaccination in comparison to the 7 …

R Kaur, JR Casey, ME Pichichero - The Pediatric infectious …, 2016 - journals.lww.com
Background: After introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in
the United States in 2000, emergence of replacement serotypes occurred, leading to the …

Dynamic changes in otopathogens colonizing the nasopharynx and causing acute otitis media in children after 13-valent (PCV13) pneumococcal conjugate …

R Kaur, N Fuji, ME Pichichero - European Journal of Clinical Microbiology …, 2022 - Springer
The otopathogens colonizing the nasopharynx (NP) and causing acute otitis media (AOM)
have shown dynamic changes following introduction of pneumococcal conjugate vaccines …

[HTML][HTML] Acute otitis media

A Danishyar, JV Ashurst - 2017 - europepmc.org
Acute Otitis Media - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech …

Effectiveness of 13-valent pneumococcal conjugate vaccination for protection against acute otitis media caused by Streptococcus pneumoniae in healthy young …

M Pichichero, R Kaur, DA Scott, WC Gruber… - The Lancet Child & …, 2018 - thelancet.com
Background With wide use of the seven-valent pneumococcal conjugate vaccine (PCV7) for
protection against acute otitis media caused by Streptococcus pneumoniae serotypes …

Single Cell Bottlenecks in the Pathogenesis of Streptococcus pneumoniae

M Kono, MA Zafar, M Zuniga, AM Roche… - PLoS …, 2016 - journals.plos.org
Herein, we studied a virulent isolate of the leading bacterial pathogen Streptococcus
pneumoniae in an infant mouse model of colonization, disease and transmission, both with …

Oral microbiota in infants fed a formula supplemented with bovine milk fat globule membranes-a randomized controlled trial

N Timby, M Domellöf, PL Holgerson, CE West… - PloS one, 2017 - journals.plos.org
Background In a recent study, supplementation of infant formula with milk fat globule
membranes (MFGM) decreased the incidence of otitis media in infants< 6 months of age …

New insights into the treatment of acute otitis media

RE El Feghaly, A Nedved, SE Katz… - Expert review of anti …, 2023 - Taylor & Francis
Introduction Acute otitis media (AOM) affects most (80%) children by 5 years of age and is
the most common reason children are prescribed antibiotics. The epidemiology of AOM has …