Adult neurogenesis in the mammalian brain: significant answers and significant questions

G Ming, H Song - Neuron, 2011 - cell.com
Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …

An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

MJ Millan - Neuropharmacology, 2013 - Elsevier
Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations

ZZ Hao, JR Wei, D Xiao, R Liu, N Xu, L Tang… - Nature …, 2022 - nature.com
The extent to which neurogenesis occurs in adult primates remains controversial. In this
study, using an optimized single-cell RNA sequencing pipeline, we profiled 207,785 cells …

METTL3-mediated m6A modification is required for cerebellar development

CX Wang, GS Cui, X Liu, K Xu, M Wang, XX Zhang… - PLoS …, 2018 - journals.plos.org
N 6-methyladenosine (m6A) RNA methylation is the most abundant modification on mRNAs
and plays important roles in various biological processes. The formation of m6A is catalyzed …

[图书][B] Understanding family change and variation: Toward a theory of conjunctural action

JA Johnson-Hanks, CA Bachrach, SP Morgan… - 2011 - books.google.com
Fertility rates vary considerably across and within societies, and over time. Over the last
three decades, social demographers have made remarkable progress in documenting these …

Orchestrating transcriptional control of adult neurogenesis

J Hsieh - Genes & development, 2012 - genesdev.cshlp.org
Stem cells have captured our imagination and generated hope, representing a source of
replacement cells to treat a host of medical conditions. Tucked away in specialized niches …

Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders

R Delgado-Morales, RC Agís-Balboa, M Esteller… - Clinical …, 2017 - Springer
Ageing is the main risk factor for human neurological disorders. Among the diverse
molecular pathways that govern ageing, epigenetics can guide age-associated decline in …

The transcription factor Zif268/Egr1, brain plasticity, and memory

A Veyrac, A Besnard, J Caboche, S Davis… - Progress in molecular …, 2014 - Elsevier
The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …

Dynamic development of thinking, feeling, and acting

HOWCS PRODUCES, FAPBY WALKING… - Handbook of child …, 2015 - books.google.com
THE POWER AND LIMITS OF SENSORIMOTOR ACTION: WHAT DOINFANTS “KNOW”
ABOUT OBJECTS AND PERSONS? 136 PATHWAYS IN THE DEVELOPMENT OF …

Early-life stress mediated modulation of adult neurogenesis and behavior

A Korosi, EFG Naninck, CA Oomen, M Schouten… - Behavioural brain …, 2012 - Elsevier
Early life is a period of unique sensitivity during which experience can confer enduring
effects on brain structure and function. During early perinatal life the quality of the …