Importance of the lipid peroxidation biomarkers and methodological aspects for malondialdehyde quantification

D Grotto, LS Maria, J Valentini, C Paniz, G Schmitt… - Quimica …, 2009 - SciELO Brasil
Free radicals induce lipid peroxidation, playing an important role in pathological processes.
The injury mediated by free radicals can be measured by conjugated dienes …

New insights in the pathogenesis of HPV infection and the associated carcinogenic processes: the role of chronic inflammation and oxidative stress

SR Georgescu, CI Mitran, MI Mitran… - Journal of …, 2018 - Wiley Online Library
Human papillomavirus (HPV) is a small double‐stranded DNA virus with tropism for
epithelial cells. To this date, over 150 genotypes are known and are classified into two major …

Aminolevulinic acid-based tumor detection and therapy: molecular mechanisms and strategies for enhancement

X Yang, P Palasuberniam, D Kraus, B Chen - International journal of …, 2015 - mdpi.com
Aminolevulinic acid (ALA) is the first metabolite in the heme biosynthesis pathway in
humans. In addition to the end product heme, this pathway also produces other porphyrin …

Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects

J Verrax, PB Calderon - Free Radical Biology and Medicine, 2009 - Elsevier
Recently, it has been proposed that pharmacologic concentrations of ascorbate (vitamin C)
can be reached by intravenous injection. Because high doses of ascorbate have been …

[HTML][HTML] Antioxidants in cervical cancer: chemopreventive and chemotherapeutic effects of polyphenols

F Di Domenico, C Foppoli, R Coccia… - Biochimica et Biophysica …, 2012 - Elsevier
Cervical cancer lesions are a major threat to the health of women, representing the second
most common cancer worldwide. The unanimously recognized etiological factor in the …

Analysis of factors affecting 5-ALA fluorescence intensity in visualizing glial tumor cells—Literature review

M Mazurek, D Szczepanek, A Orzyłowska… - International journal of …, 2022 - mdpi.com
Glial tumors are one of the most common lesions of the central nervous system. Despite the
implementation of appropriate treatment, the prognosis is not successful. As shown in the …

Mercury exposure and oxidative stress in communities of the Brazilian Amazon

D Grotto, J Valentini, M Fillion, CJS Passos… - Science of the total …, 2010 - Elsevier
This study was designed to assess possible associations between biomarkers of mercury
(Hg) exposure and oxidative stress in fish-eating Amazonian communities. Clinical samples …

Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations

JBT Rocha, RA Saraiva, SC Garcia… - Toxicology …, 2012 - academic.oup.com
Abstract δ-ALA-D is a metalloenzyme that has 3 vicinal thiol/thiolate groups that coordinate
with Zn (ii). The proximity between the sulfhydryl groups renders δ-ALA-D extremely …

Oxidative stress in cervical cancer pathogenesis and resistance to therapy

S Ebrahimi, A Soltani… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer (CC) is one of the most common cancers among females, and it is most
notable in developing countries. The exact etiology of CC is poorly understood; but …

Dual role of heme iron in cancer; promotor of carcinogenesis and an inducer of tumour suppression

SMK Gamage, KTW Lee, DLO Dissabandara… - Experimental and …, 2021 - Elsevier
Purpose Heme is a crucial compound for cell survival but is also equipped with the potential
to be toxic and carcinogenic to cells. However, with the recent advancement of knowledge …